494-47-3

Basic information

• Product Name: HYDROFURAMIDE
• Synonyms: 1-(2-furanyl)-n,n’-bis(2-furanylmethylene)-methanediamin;2-(bis(furfurylidenamino))methylfuran;ba51-90222;furfuramide;n,n’-difurfurylidene-2-furanmethanediamin;HYDROFURAMIDE;1,3,5-tri(2-furyl)-2,4-diazapenta-1,4-diene;N,N'-Difurfurylidene(2-furyl)methanediamine
• CAS NO: 494-47-3
• Molecular Formula: C₁₅H₁₂N₂O₃
• Molecular Weight: 268.27
• EINECS: 207-790-8
• Mol File: 494-47-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 117°
• Boiling Point: bp ~250° with decompn
• Flash Point: 157.372°C
• Appearance: /
• Density: 1.1992 (rough estimate)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5906 (estimate)
• CAS DataBase Reference: HYDROFURAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HYDROFURAMIDE(494-47-3)
• EPA Substance Registry System: HYDROFURAMIDE(494-47-3)

Safety Data

• Hazardous Substances Data: 494-47-3(Hazardous Substances Data)

Usage

Chemical Properties

Light-brown to white powder.Insoluble in cold water; soluble in alcohol and ether.

Uses

Vulcanization accelerator.

InChI:InChI=1/C15H12N2O3/c1-4-12(18-7-1)10-16-15(14-6-3-9-20-14)17-11-13-5-2-8-19-13/h1-11,15H/b16-10+,17-11u

Upstream product

• 98-01-1 furfural 

Downstream Products

• 4795-29-3 TETRAHYDROFURFURYLAMINE 
• 5343-16-8 di-(2-tetrahydrofurfurylmethyl)amine 
• 18240-50-1 bis((furan-2-yl)methyl)amine 
• 617-89-0 furan-2-ylmethanamine 
• 135822-87-6 (E)-N-(furan-2-ylmethylene)-4-methylbenzenesulfonamide 
• 14744-31-1 (E)-N-(furan-2-ylmethylene)benzenesulfonamide 
• 98-01-1 furfural 

Relevant articles and documents

Self-regulated catalysis for the selective synthesis of primary amines from carbonyl compounds

Most current processes for the general synthesis of primary amines by reductive amination are performed with enormously excessive amounts of hazardous ammonia. It remains unclear how catalysts should be designed to regulate amination reaction dynamics at a low ammonia-to-substrate ratio for the quantitative synthesis of primary amines from the corresponding carbonyl compounds. Herein we show a facile control of the reaction selectivity in the layered boron nitride supported ruthenium catalyzed reductive amination reaction. Specifically, locating ruthenium to the edge surface of layered boron nitride leads to an increased hydrogenation activity owing to the enhanced interfacial electronic effects between ruthenium and the edge surface of boron nitride. This enables self-accelerated reductive amination reactions which quantitatively synthesize structurally diverse primary amines by reductive amination of carbonyl compounds with twofold ammonia. This journal is

Exploration of the Role of Double Schiff Bases as Catalytic Intermediates in the Knoevenagel Reaction of Furanic Aldehydes: Mechanistic Considerations

This paper presents mechanistic considerations on an efficient, green, and solvent-free Knoevenagel procedure for the chemical transformation of furanic aldehydes into their corresponding α,β-unsaturated compounds. In the proposed mechanism furanic aldehydes react with ammonia, released from ammonium salts, to form a catalytically active double Schiff base. The catalytic intermediates involved in the condensation step are characterized.

Studies on the reaction of diimines with thiourea: Synthesis and solvent-induced cis/trans-isomerization of 1,3,5-triazinane-2-thiones

The reaction of N,Nc-bis(arylmethylidene)arylmethane diimines with thiourea under reflux in methanol was studied. The reaction gave a diastereomeric mixture of 4,6-disubstituted 1,3,5-triazinane-2-thiones in good yields. Two diastereoisomers of 4,6-diphenyl-1,3,5-triazinane-2-thione were detected in a solution of CDCl3 by NMR analysis. According to the NMR studies, the cisdiastereoisomer undergoes a solvent-induced cis/trans-isomerization process, producing the trans-diastereoisomer in DMSO. The stereochemistry of the trans-diastereoisomer was determined by Xray crystallographic analysis.