494-48-4Relevant academic research and scientific papers
USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION
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, (2010/12/18)
The present invention primarily relates to the use of specific compounds of formula (I) or of specific salts of a compound of formula (I) or mixtures thereof for synergistically enhancing the sweet taste of a sweet-tasting substance.
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA
Oslund, Rob C.,Cermak, Nathan,Verlinde, Christophe L.M.J.,Gelb, Michael H.
supporting information; experimental part, p. 5415 - 5419 (2009/05/30)
Simplified analogs of YM-26734, a known inhibitor of secreted phospholipase A2 (sPLA2) group IIA, were synthesized and found to also display potent inhibition at low nanomolar concentrations. Analogs were based on the didodecanoylphl
Studies on flavans. III. The total synthesis of (±)-7,4′ -dihydroxy-3′-methoxyflavan, (±)-7,3′-dihydroxy-4′ -methoxyflavan, and (±)-7,4′-dihdroxyflavan
Xue, Jijun,Zhang, Xianshu,Chen, Xuesong,Zhang, Yingpeng,Li, Ying
, p. 3527 - 3536 (2007/10/03)
The first total synthesis of (±)-7,3′-dihydroxy-4′ -methoxyflavan (1) and (±)-7,4′-dihydroxy-3′-methoxyflavan (2), along with the synthesis of (±)-7,4′-dihydroxyflavan (3), three naturally occurring flavans, were described. The key step is the cyclization of 1,3-diaryl-1-propanol by BF3·Et2O.
Identification of three hydroxyflavan phytoalexins from daffodil bulbs
Coxon, David T.,O'Neill, Timothy M.,Mansfield, John W.,Porter, Alexander E.A.
, p. 889 - 891 (2007/10/02)
Three phytoalexins were isolated from daffodil bulb scales inoculated with Botrytis cinerea and identified as 7-hydroxyflavan, 7,4′-dihydroxyflavan and 7,4′-dihydroxy-8-methylflavan. The structures of the phytoalexins were confirmed by total synthesis.
