251909-34-9Relevant academic research and scientific papers
The novel flavan-3-ol, (2R,3S)-guibourtinidol and its diastereomers
Nel, Reinier J.J.,Mthembu, Makhosazana,Coetzee, Johan,Van Rensburg, Hendrik,Malan, Elfranco,Ferreira, Daneel
, p. 1153 - 1158 (1999)
The novel (2R,3S)-guibourtinidol, representing the first flavan-3-ol with 4',7-dihydroxy phenolic substitution pattern, was identified in the heartwood of Cassia abbreviata. Asymmetric dihydroxylation of (E)-1-(4'-O- methoxymethylphenyl)-3-(2',4'-di-O-met
Studies on flavans. III. The total synthesis of (±)-7,4′ -dihydroxy-3′-methoxyflavan, (±)-7,3′-dihydroxy-4′ -methoxyflavan, and (±)-7,4′-dihdroxyflavan
Xue, Jijun,Zhang, Xianshu,Chen, Xuesong,Zhang, Yingpeng,Li, Ying
, p. 3527 - 3536 (2007/10/03)
The first total synthesis of (±)-7,3′-dihydroxy-4′ -methoxyflavan (1) and (±)-7,4′-dihydroxy-3′-methoxyflavan (2), along with the synthesis of (±)-7,4′-dihydroxyflavan (3), three naturally occurring flavans, were described. The key step is the cyclization of 1,3-diaryl-1-propanol by BF3·Et2O.
