494222-00-3

Upstream product

• 686318-93-4 C₁₃H₂₁NO₄ 
• 41349-38-6 methyl 7-bromohept-5-ynoate 
• 50781-91-4 methyl 7-hydroxy-5-heptynoate 
• 41300-59-8 7-Hydroxy-5-heptynoic Acid 
• 53293-00-8 hex-5-ynoic acid 
• 1369917-53-2 methyl (5Z)-7-[(2R)-2-{(1E)-4-[3-(methoxymethyl)phenyl]-3-oxo-1-buten-1-yl}-5-oxo-1-pyrrolidinyl]-5-heptenoate 
• 685835-25-0 methyl 7-{(2R)-2-[(tert-butyldimethylsilyloxy)methyl]-5-oxo-1-pyrrolidinyl}-5-heptynoate 

Relevant academic research and scientific papers

Discovery of an 8-aza-5-thiaProstaglandin E1 analog as a highly selective EP4 receptor agonist

For the purpose of discovering an orally available EP4 subtype-selective agonist, a series of 8-aza prostaglandin E1 (PGE1) analogs were synthesized and evaluated for their affinity for PGE2 receptor subtypes. Additionally

REMEDIES FOR DISEASES WITH BONE MASS LOSS HAVING EP sb 4 /sb AGONIST AS THE ACTIVE INGREDIENT

A pharmaceutical composition for topical administration for prevention and/or treatment of diseases associated with decrease in bone mass comprising an EP4 agonist as an active ingredient. An EP4 agonist, in which includes a compound