4946-28-5Relevant academic research and scientific papers
Thio radical-induced denitrogenative annulation of 1-azido-2-isocyanoarenes to construct 2-thiolated benzimidazoles
Li, Dengke,Lei, Jian
supporting information, p. 9666 - 9671 (2019/11/20)
A method for the synthesis of 2-thiolated benzimidazoles is described starting from thiols and 1-azido-2-isocyanoarenes. The isocyano group works as an acceptor of various thio radicals, followed by denitrogenative annulation of the resulting imidoyl radi
Chemoselective Chan-Lam Coupling Reactions between Benzimidazoline-2-thiones and Arylboronic Acids
Liu, Xing,Dong, Zhi-Bing
, p. 11524 - 11532 (2019/10/02)
An efficient Chan-Lam-type methodology for the selective synthesis of S-arylbenzimidazoles and N,S-diarylbenzimidazoles was developed. The selectivity was controlled by varying the amount of the catalyst Cu(OAc)2·H2O, temperature, an
Ligand-Free CuI-Catalyzed Chemoselective S-Arylation of 2-Mercaptobenzimidazole with Aryl Iodides
Tan, Bryan Yong-Hao,Teo, Yong-Chua
supporting information, p. 2056 - 2060 (2018/09/18)
A practical and efficient strategy for the chemoselective C-S cross-coupling of 2-mercaptobenzimidazole derivatives with a range of substituted aryl iodides is described. Under the optimized conditions of 5 mol% CuI and 100 °C, a variety of S-arylated products were obtained in good to excellent yields (up to 92 %) without the need for assisting ligands.
S-arylation of mercaptobenzimidazoles using Cu(I) catalysts - Experimental and theoretical observations
Sekar, Ramkumar,Srinivasan, Marutheeswaran,Marcelis, Antonius T.M.,Sambandam, Anandan
experimental part, p. 3347 - 3352 (2011/06/28)
Substituted 2-mercaptobenzimidazoles (MBI) are an important class of bio-active and industrially important organic compounds. In this Letter, a new synthetic method is presented for the selective S-arylation of MBI with substituted aryl iodides using low
