86652-69-9

Basic information

• Product Name: 2-azido-4-(tert-butyl)-1-isocyanobenzene
• Synonyms: 2-azido-4-(tert-butyl)-1-isocyanobenzene
• CAS NO: 86652-69-9
• Molecular Weight: 144.136
• Mol File: 86652-69-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-azido-4-(tert-butyl)-1-isocyanobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-4-(tert-butyl)-1-isocyanobenzene(86652-69-9)
• EPA Substance Registry System: 2-azido-4-(tert-butyl)-1-isocyanobenzene(86652-69-9)

Safety Data

• Hazardous Substances Data: 86652-69-9(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 1005-07-8 o-azidoaniline 
• 62-53-3 aniline 
• 1410063-73-8 2-azido-4-(tert-butyl)aniline 
• 118-92-3 anthranilic acid 
• 31162-13-7 2-azidobenzoic acid 
• 33263-03-5 2-azidobenzoic amide 
• 86652-68-8 N-formyl-2-azidoaniline 

Downstream Products

• 1235454-77-9 3-phenyl-4-(trifluoromethyl)-[1,2,3]triazolo[1,5-a]quinoxaline 
• 705-09-9 2-(difluoromethyl)-1H-benzo[d]imidazole 
• 4946-28-5 2-[(4-methylphenyl)sulfanyl]-1H-benzimidazole 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 1201128-96-2 [Ru(η5-C5H5)(1,2-bis(diphenylphosphino)ethane)(2-azidophenyl isocyanide)]Cl 
• 1111682-40-6 ((CH₃)2CHC₆H₄CH₃)RuCl₂(CNC₆H₄N₃) 

Relevant articles and documents

A one-pot synthesis of [1,2,3]triazolo[1,5-a]quinoxalines from 1-azido-2-isocyanoarenes with high bond-forming efficiency

An efficient approach to prepare 1,2,3-triazolo[1,5-a]quinoxaline scaffolds, starting from 1-azido-2-isocyanoarenes and terminal acetylenes or substituted acetaldehydes, has been developed. In the case of trifluoromethylation triggered cyclization, four chemical bonds, including two C-C and two C-N bonds, were formed consecutively without isolating the triazole intermediate. In addition, these triazo-fused products were readily transformed into diversified quinoxaline derivatives via rhodium-catalyzed carbenoid insertion reactions.

Template synthesis of benzannulated N-heterocyclic carbene ligands

The reaction of 2-azidophenyl isocyanide (7) with [M(CO)5(thf)] (M = Cr, W) yields the isocyanide complexes [M(CO)5(7)] (M = Cr 8, M = W 9). Complexes 8 and 9 react with tertiary phosphines such as triphenylphosphane at the azido fun