494747-95-4

Upstream product

• 271-63-6 7-Azaindole 
• 494747-91-0 7-benzhydroxy-3-(4-bromo-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)indole-1-carboxylic acid tert-butyl ester 
• 494747-90-9 3-(7-benzhydroxy-1H-indol-3-yl)-4-bromo-1-methylpyrrole-2,5-dione 
• 135328-49-3 7-(diphenylmethoxy)indole 
• 3005-27-4 3,4-dibromo-1-methyl-2,5-dihydropyrrole-2,5-dione 

Downstream Products

• 494747-98-7 6-methyl-11-benzhydryloxy-13H-pyrrolo[2,3-a]pyrrolo[3,4-c]pyrido[3',2':4,5]carbazole-5,7-dione-12-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 7-azaindolocarbazoles

In the course of a program aimed at designing antitumor agents containing an indolocarbazole framework, an efficient synthetic scheme based on the use of 3,4-dibromo-N-methylmaleimide and 7-azaindole has been developed to elaborate a series of mono- and di-aza derivatives of arcyriaflavin. The procedure was further exploited to introduce a hydroxyl group at different positions on the indole moiety of the non-symmetrical compounds. The DNA binding capacity and cytotoxic potential of these 7-azaindolocarbazole derivatives was evaluated.