494783-54-9

Upstream product

• 494783-50-5 tert-butyl 4-[(4R)-2-oxo-4-benzyl(1,3-oxazolidin-3-yl)](3S)-3-[(4-chlorophenyl)methyl]-4-oxobutanoate 
• 678995-20-5 N-[2-(4-benzyl-piperazin-1-yl)-phenyl]-N-cyclopropylmethyl-methanesulfonamide 
• 494783-49-2 (4R)-3-[3-(4-chlorophenyl)propanoyl]-4-benzyl-1,3-oxazolidin-2-one 
• 494783-46-9 N-cyclopropylmethyl-N-(2-piperazin-1-yl-phenyl)-methanesulfonamide 
• 494783-51-6 (2S)-3-[(tert-Butyl)-oxycarbonyl]-2-[(4-chlorophenyl)methyl]-propanoic acid 
• 199105-18-5 N-[2-(4-Benzyl-piperazin-1-yl)-phenyl]-methanesulfonamide 
• 52085-96-8 3-(4-chlorophenyl)propanoyl chloride 
• 494783-53-8 tert-butyl (3S)-3-[(4-chlorophenyl)-methyl]-4-(4-{2-[(cyclopropylmethyl)(methylsulfonyl)-amino]phenyl}-piperazinyl)-4-oxobutanoate 

Downstream Products

• 494783-55-0 tert-butyl 4-[(3S)-3-[(4-chlorophenyl)methyl]-4-(4-{2-[(cyclopropylmethyl)(methylsulfonyl)amino]-phenyl}piperazinyl)-4-oxobutanoyl]piperazinecarboxylate 

Relevant academic research and scientific papers

Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core

A novel series of piperazines appended to a succinamide backbone were synthesized and found to have a high affinity for the melanocortin-4 receptor (IC50s ranging from 0.1 to 200 nM). Both agonists and antagonists of MC4R were prepared by modi

Substituted piperazines and methods of use

Selected substituted piperazine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical com