4949-24-0

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 15 carbon (C) atoms, 13 hydrogen (H) atoms, and 5 nitrogen (N) atoms.

Explanation

Triazole compounds are a class of organic compounds characterized by a five-membered ring containing three nitrogen atoms. This specific compound belongs to this class.

Explanation

The compound is unique because it has two phenyl groups (C6H5) attached to the nitrogen atoms at positions 1 and 5 on the triazole ring, which differentiates it from other triazole compounds.

Explanation

The compound is used in the synthesis of various pharmaceuticals, indicating its importance in the development of new drugs.

Explanation

The compound can act as a ligand, which is a molecule that donates one or more electrons to a central atom to form a coordination complex. This property makes it useful in coordination chemistry.

Explanation

Due to its structural and functional properties, the compound has potential applications in medicinal chemistry for the development of new drugs and in material science for the creation of new materials with specific properties.

Explanation

The compound is classified as an organic compound because it contains carbon and hydrogen atoms, along with other elements like nitrogen in its structure.

Class

Triazole compounds

Unique feature

Two phenyl groups attached to nitrogen atoms at positions 1 and 5

Application

Synthesis of pharmaceuticals

Role

Ligand in coordination chemistry

Potential applications

Medicinal chemistry and material science

Organic compound

Yes

Upstream product

• 62-53-3 aniline 
• 4921-82-8 1-benzoyl-3-phenylthiourea 
• 98-88-4 benzoyl chloride 
• 1612-76-6 2-amino-5-phenyl-1,3,4-oxadiazole 
• 532-55-8 Benzoyl isothiocyanate 
• 64341-79-3 N-phenylthiocarbamoyl-benzimidic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 3-amino-1,2,4-triazole derivatives as potential anticancer compounds

Two series of compounds carrying 3-amino-1,2,4-triazole scaffold were synthesized and evaluated for their anticancer activity against a panel of cancer cell lines using XTT assay. The 1,2,4-triazole synthesis was revisited for the first series of pyridyl derivatives. The biological results revealed the efficiency of the 3-amino-1,2,4-triazole core that could not be replaced and a clear beneficial effect of a 3-bromophenylamino moiety in position 3 of the triazole for both series (compounds 2.6 and 4.6) on several cell lines tested. Moreover, our results point out an antiangiogenic activity of these compounds. Overall, the 5-aryl-3-phenylamino-1,2,4-triazole structure has promising dual anticancer activity.

Easy access to triazoles, triazolopyrimidines, benzimidazoles and imidazoles from imidates

We have described a new and easy synthesis of triazoles, triazolopyrimidines, benzimidazoles and imidazoles variously substituted based on the reaction of imidates with diamine derivatives. The products were obtained in moderate to good yields. A general mechanism for the reactions is proposed.

A convenient and efficient method for the synthesis of mono- and N,N-disubstituted thioureas

A convenient method for the synthesis of mono- and N,N-disubstituted thioureas by the debenzoylation of N-substituted- and N,N-disubstituted- N′-benzoylthioureas with hydrazine hydrate under solvent-free conditions has been developed. N-Substituted-N′-benzoylthioureas and hydrazine hydrate were mixed, and stirred at room temperature without a solvent to give the corresponding N-substituted thioureas in high yields.