4949-45-5

Basic information

• Product Name: BENZYL 3-OXOPENTANOATE
• Synonyms: BENZYL 3-OXOPENTANOATE
• CAS NO: 4949-45-5
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Mol File: 4949-45-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZYL 3-OXOPENTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL 3-OXOPENTANOATE(4949-45-5)
• EPA Substance Registry System: BENZYL 3-OXOPENTANOATE(4949-45-5)

Safety Data

• Hazardous Substances Data: 4949-45-5(Hazardous Substances Data)

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 14447-18-8 benzyl 2-cyanoacetate 
• 100-51-6 benzyl alcohol 
• 4949-44-4 ethyl propanoylacetate 
• 141-97-9 ethyl acetoacetate 
• 30414-53-0 methyl propanoyl acetate 
• 481014-56-6 (±)-benzyl penta-2,3-dienoate 

Downstream Products

• 128773-38-6 benzyl 3-ethyl-4-t-butoxycarbonyl-5-methyl-pyrrole-2-carboxylate 
• 179482-13-4 5-(benzyloxycarbonyl)-1,6-dihydro-2-methoxy-4-ethyl-6-(3,4-di-fluorophenyl)pyrimidine 
• 86978-73-6 benzyl 2-diazo-3-oxopentanoate 
• 1365386-49-7 cyclohexylmethyl 6-ethyl-4-(3-hydroxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1224680-12-9 C₂₆H₃₄N₂O₄Si 
• 1224680-13-0 C₁₉H₂₈N₂O₄Si 
• 1224680-14-1 (S)-4-(3-(tert-butyldimethylsilyloxy)phenyl)-6-ethyl-2-oxo-1,2,3,4-tetrahydropyrimidin-5-carboxylic acid 
• 191353-82-9 5-(Benzyloxycarbonyl)-4-ethyl-1,6-dihydro-2-methoxy-6-(2,4-difluorophenyl)-1-[(4-nitrophenyloxy)-carbonyl]pyrimidine 
• 191353-81-8 5-(benzyloxycarbonyl)-1,6-dihydro-2-methoxy-4-ethyl-6-(2,4-difluorophenyl)pyrimidine 

Relevant articles and documents

Oxone-promoted hydration of electron-deficient allenic esters and ketones into 1,3-dicarbonyl compounds

Abstract A novel and mild protocol for the hydration of electron-deficient allenic esters and ketones into various 1,3-dicarbonyl compounds is described. The hydration of allenes promoted by oxone in DMF afforded the corresponding products in moderate to good yields. This work features the employment of only a catalytic amount of inexpensive and nontoxic solid reagent oxone (2KHSO5·KHSO4·K2SO4), avoiding the utility of toxic metals or traditional Br?nsted acids, in a green version of viewpoint. A possible reaction mechanism for this transformation is also primarily proposed.

Layered double hydroxides-supported diisopropylamide: Synthesis, characterization and application in organic reactions

The layered double hydroxides-supported diisopropylamide (LDH-DA) catalyst is found to be an efficient and selective solid base for aldol, Knoevenagel, Henry, Michael, transesterification and epoxidation reactions under liquid phase conditions. LDH-DA is synthesized by the interaction of lithium diisopropylamide with LDH-NO3 (as-synthesized) and calcined LDH-NO3. The LDH-DA (Mg/Al, 3/1) and their precursors are well characterized by using various instrumental techniques such as FT-IR, TGA and DTA, powder XRD, solid state 27Al MAS NMR spectroscopy, SEM and XPS (ESCA).

A general synthesis of dioxolenone prodrug moieties

A general method for the synthesis of dioxolenone prodrug moieties from appropriately substituted β-ketoesters is described. This novel and versatile sequence allows for the synthesis of alkyl- or aryl-substituted dioxolenone alcohols 8 or bromides 9. Coupling of the bromides 9 to prepare bis-dioxolenone phosphonate prodrug esters is also presented.