4950-01-0

Basic information

• Product Name: N,O-BIS-(BENZYLOXYCARBONYL)-HYDROXYLAMINE
• Synonyms: N,O-BIS-(BENZYLOXYCARBONYL)-HYDROXYLAMINE
• CAS NO: 4950-01-0
• Molecular Formula: C₁₆H₁₅NO₅
• Molecular Weight: 301.29
• Mol File: 4950-01-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,O-BIS-(BENZYLOXYCARBONYL)-HYDROXYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,O-BIS-(BENZYLOXYCARBONYL)-HYDROXYLAMINE(4950-01-0)
• EPA Substance Registry System: N,O-BIS-(BENZYLOXYCARBONYL)-HYDROXYLAMINE(4950-01-0)

Safety Data

• Hazardous Substances Data: 4950-01-0(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 3426-71-9 Benzyl N-hydroxycarbamate 

Downstream Products

• 62995-07-7 Benzyl (dimethyl(oxo)-λ⁶-sulfaneylidene)carbamate 
• 172747-45-4 N-Hydroxy-N-[1-[4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]phenyl]ethyl]urea 
• 1172627-09-6 C₂₃H₂₇NO₆ 
• 1172627-08-5 C₂₂H₂₅NO₆ 
• 1172627-07-4 C₂₁H₂₃NO₆ 
• 1172627-06-3 C₂₀H₂₁NO₆ 
• 1172627-10-9 C₂₅H₂₉NO₆ 
• 203728-15-8 benzyl N-hydroxy(N-benzyl)carbamate 
• 645389-99-7 (2S,4R)-(+)-4-triisopropylsiloxy-2-(4'-N,O-di(benzyloxycarbonyl)hydroxylaminobutyl)cyclopentan-1-one 
• 346461-21-0 C₂₄H₂₃NO₅ 
• 346461-16-3 C₂₂H₂₃NO₅ 

Relevant articles and documents

IMPROVED AMINOHYDROXYLATION OF ALKENES

The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.

Investigating the reaction of N-carbobenzoxy-O-carbobenzoxy-hydroxylamine with dimethyl sulfoxide: Formation of S,S-dimethyl-N-[(phenylmethoxy)-carbonyl] sulfoximine

N-Carbobenzoxy-O-carbobenzoxyhydroxylamine (1a) underwent a thermally induced reaction in DMSO in which there is net N-α-eliminative oxidation with tandem oxidative incorporation of DMSO to yield S,S-dimethyl-N-[(phenyl- methoxy)carbonyl]sulfoximine. Mech

Highly efficient Friedel-Crafts-type benzylation via benzyl cations generated in multiple spacer-molecule separated ion-pairs

Deamination, as a facile route to highly reactive carbocations, is of interest to several areas of organic chemistry, industry, and medicine. The reactivity and utility of these carbocations derives from the presence of a lone nitrogenous entity (N2or N2O) interposed between the ion-pair. We report here the synthesis of a new deamination precursor whose nitrosation and subsequent decomposition constitutes a novel deamination method. In this novel approach, multiple spacer-molecules are generated in the inter-ion space. The resultant cations are exceedingly reactive but are longer-lived than carbocations derived from standard deaminations. The result is nearly quantitative yields of solvent-derived products from even poorly nucleophilic solvents such as benzene, toluene, and mesitylene.

A survey of suitable protecting groups for the synthesis of hydroxylamines by Mitsunobu reactions

A variety of protecting groups, commonly associated with peptide synthesis, are suitable for the N,O-protection of hydroxylamine; the resulting reagents are all suitable for N-alkylhydroxylamine synthesis using the Mitsunobu method.

Antibacterial agents

Compounds of the formula (II): STR1 wherein A is a group such that CO2 A is carboxylic acid, a non-toxic salt thereof or non-toxic ester thereof; R1 is COR4 or OR5 wherein R4 is lower alkyl, lower alk