4950-06-5

Basic information

• Product Name: 2,3-DIBROMO-4,5-DIHYDROXYBENZYL ALCOHOL
• Synonyms: LANESOL;LANASOL;2,3-DIBROMO-4,5-DIHYDROXYBENZYL ALCOHOL;lanosol;2,3-Dibromo-4,5-dihydroxybenzenemethanol;3,4-Dibromo-5-(hydroxymethyl)-1,2-benzenediol;3,4-Dibromo-5-(hydroxymethyl)benzene-1,2-diol;3,4-Dibromo-5-(hydroxymethyl)catechol
• CAS NO: 4950-06-5
• Molecular Formula: C₇H₆Br₂O₃
• Molecular Weight: 297.93
• EINECS: 225-594-0
• Product Categories: Aromatic Phenols
• Mol File: 4950-06-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 408.8°Cat760mmHg
• Flash Point: 201°C
• Appearance: /
• Density: 2.248g/cm³
• Vapor Pressure: 2.05E-07mmHg at 25°C
• Refractive Index: 1.711
• CAS DataBase Reference: 2,3-DIBROMO-4,5-DIHYDROXYBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIBROMO-4,5-DIHYDROXYBENZYL ALCOHOL(4950-06-5)
• EPA Substance Registry System: 2,3-DIBROMO-4,5-DIHYDROXYBENZYL ALCOHOL(4950-06-5)

Safety Data

• Hazardous Substances Data: 4950-06-5(Hazardous Substances Data)

Usage

General Description

2,3-Dibromo-4,5-dihydroxybenzyl alcohol, also known as 2,3-Dibromo-4,5-dihydroxybenzyl alcohol, is a chemical compound that is used primarily as an intermediate in organic synthesis. It is a white to off-white solid that is soluble in water and ethanol, and is known for its antibacterial and antiviral properties. It is commonly used as a reagent in the synthesis of pharmaceuticals and other organic compounds. Additionally, 2,3-Dibromo-4,5-dihydroxybenzyl alcohol is used as an antioxidant and preservative in various products, such as cosmetics, food, and pharmaceuticals, due to its ability to inhibit the growth of microorganisms.

InChI:InChI=1/C7H6Br2O3/c8-5-3(2-10)1-4(11)7(12)6(5)9/h1,10-12H,2H2

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 121-33-5 vanillin 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 2973-75-3 5,6-dibromo-4-hydroxy-3-methoxybenzaldehyde 
• 40089-29-0 dipotassium 2,3-dibromo-5-hydroxybenzyl-1',4-disulfate 
• 14045-41-1 2,3-dibromo-4,5-dihydroxybenzylaldehyde 

Downstream Products

• 100676-08-2 methylrhodomelol 
• 70625-32-0 3,4-Dibrom-5,5'-methylendibrenzcatechin 
• 70625-30-8 5-(2-(2,3-dibromo-4,5-dihydroxybenzyl)-4,5-dihydroxybenzyl)-3,4-dibromobenzene-1,2-diol 
• 65487-78-7 3,4,3',4'-Tetrabrom-5,5'-methylendibrenzcatechin-tetramethylether 
• 65487-76-5 2,2′,3,3′-tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane 
• 14045-42-2 3,4-dibromo-5-(methoxymethyl)benzene-1,2-diol 
• 54502-93-1 3,4-dibromo-5-(ethoxymethyl)benzene-1,2-diol 
• 100676-10-6 rhodomelol 

Relevant articles and documents

Total synthesis of the biologically active, naturally occurring 3,4-dibromo-5-[2-bromo-3,4-dihydroxy-6-(methoxymethyl)benzyl]benzene-1,2-diol and regioselective O-demethylation of aryl methyl ethers

3,4-Dibromo-5-[2-bromo-3,4-dihydroxy-6-(methoxymethyl)benzyl]benzene-1, 2-diol (2), a natural product, has been synthesized for the first time starting from (3-bromo-4,5-dimethoxyphenyl)methanol (5) in five steps and with an overall yield of 34%. The reaction of some methoxymethyl-substituted aryl methyl ethers with BBr3, followed by the addition of MeOH, afforded the corresponding methoxymethyl-substituted arylphenols in high yields.

Synthesis of some hydroxymethylbromophenols of marine origin

The hydroxymethylbromophenols 5, 7 and 9, isolated from marine source have been prepared in good yield.The bromo derivatives 1 and 2 of vanillin are demethylated to 4 and 6 which on borohydride reduction furnish 5 and 7 respectively.The dibromo-p-cresol (3) is oxidised to the aldehyde 8 which on borohydride reduction affords 9.