14045-42-2

Basic information

• Product Name: 3,4-dibromo-5-(methoxymethyl)benzene-1,2-diol
• Synonyms: 1,2-benzenediol, 3,4-dibromo-5-(methoxymethyl)-
• CAS NO: 14045-42-2
• Molecular Formula: C₈H₈Br₂O₃
• Molecular Weight: 311.9553
• Mol File: 14045-42-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 347.6°C at 760 mmHg
• Flash Point: 164°C
• Density: 1.976g/cm³
• Vapor Pressure: 2.66E-05mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 3,4-dibromo-5-(methoxymethyl)benzene-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dibromo-5-(methoxymethyl)benzene-1,2-diol(14045-42-2)
• EPA Substance Registry System: 3,4-dibromo-5-(methoxymethyl)benzene-1,2-diol(14045-42-2)

Safety Data

• Hazardous Substances Data: 14045-42-2(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 14045-41-1 2,3-dibromo-4,5-dihydroxybenzylaldehyde 
• 67-56-1 methanol 
• 4950-06-5 lanosol 
• 40089-29-0 dipotassium 2,3-dibromo-5-hydroxybenzyl-1',4-disulfate 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 2973-75-3 5,6-dibromo-4-hydroxy-3-methoxybenzaldehyde 

Relevant articles and documents

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In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers

Bioassay-guided fractionation was applied to the cytotoxic chloroform fraction of the red alga Polysiphonia lanosa. The major compounds of the most active fraction were identified using GLC-MS analysis as lanosol (1), methyl, ethyl, and n-propyl ethers of lanosol (1a, 1b, and 1c, respectively), and aldehyde of lanosol (2), although 1b appears to be an artifact arising during the fractionation procedure. These compounds and other known bromophenols were synthesized in addition to four novel isomers (3, 3a-c). The cytotoxic activities of all the synthetic compounds were determined against DLD-1 cells using the MTT assay. Compounds with IC50 50 = 1.72 and 0.80 μmol, respectively), and its effect on the cell cycle was studied using flow cytometry.