495412-82-3Relevant academic research and scientific papers
Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: Differences of bioactivity in the enantiomeric series
Mente, Nolan R.,Wiemer, Andrew J.,Neighbors, Jeffrey D.,Beutler, John A.,Hohl, Raymond J.,Wiemer, David F.
, p. 911 - 915 (2007/10/03)
Total synthesis of the (R,R,R)- and (S,S,S)-enantiomers of the natural product schweinfurthin F has been completed. Comparisons of spectral data and optical rotations with those reported for the natural product, as well as a variety of bioassay data, allo
Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
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, (2008/06/13)
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
