495415-08-2

Usage

Uses

Used in Pharmaceutical Industry:
1,4-Piperidinedicarboxylic acid, 4-Methoxy-, 1-(1,1-diMethylethyl) 4-Methyl ester is used as a chemical intermediate for the synthesis of new drugs for various medical conditions. Its unique structure and functional groups make it a promising candidate for drug development, potentially leading to innovative treatments and therapies.

Upstream product

• 495415-09-3 1-tert-butyl 4-methyl 4-hydroxypiperidine-1,4-dicarboxylate 
• 74-88-4 methyl iodide 

Downstream Products

• 1190314-13-6 4-methoxypiperidine-4-carboxylic acid methyl ester hydrochloride 

Relevant academic research and scientific papers

INHIBITORS OF MUTANT FORMS OF EGFR

The present disclosure provides a compound represented by structural formula (I) : or a pharmaceutically acceptable salt thereof useful for treating a cancer.

HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS

Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein R1, R2, R4, R5, R6, R7, R8, R9, R10,Z, X1, X2, X3, L2, HET, n and q are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.