49553-16-4Relevant articles and documents
Improved method for synthesizing L-thyroxine sodium
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Paragraph 0041; 0043; 0045; 0046; 0066; 0067; 0069; 0071, (2019/06/11)
The invention relates to an improved method for synthesizing L-thyroxine sodium. The improved method includes the steps that 3,5-diiodomethane-L-tyrosine is used as a raw material, and then subjectedto a copper complex reaction, a coupling reaction, an acid hydrolysis reaction, an iodine generation reaction and a salt forming reaction to obtained the L-thyroxine sodium. According to the improvedmethod for synthesizing the L-thyroxine sodium, the yield of the L-thyroxine sodium can be improved, the product cost is lowered, and industrialization is convenient.