4956-37-0

Basic information

• Product Name: Oestradiol 17-heptanoate
• Synonyms: oestradiol 17-heptanoate;1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 17-ENANTHATE;17BETA-ESTRADIOL ENANTHATE;17BETA-ESTRADIOL HEPTANOATE;17-BETA-ESTRADIOL 17-ENANTHATE;17-BETA-ESTRADIOL 17-HEPTANOATE;3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 17-ENANTHATE;estra-1,3,5(10)-triene-3,17b-diol 17-heptanoate
• CAS NO: 4956-37-0
• Molecular Formula: C₂₅H₃₆O₃
• Molecular Weight: 384.55
• EINECS: 225-599-8
• Product Categories: Steroids;API;progestogen estrogen;Hormone Drugs
• Mol File: 4956-37-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 94-96°
• Boiling Point: 509.5 °C at 760 mmHg
• Flash Point: 197.1 °C
• Appearance: white crystalline powder
• Density: 1.11 g/cm³
• Vapor Pressure: 5.27E-11mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.25±0.60(Predicted)
• Merck: 14,3703
• CAS DataBase Reference: Oestradiol 17-heptanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Oestradiol 17-heptanoate(4956-37-0)
• EPA Substance Registry System: Oestradiol 17-heptanoate(4956-37-0)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 22-36
• Hazardous Substances Data: 4956-37-0(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 4956-37-0 differently. You can refer to the following data:
1. Estrogen.
2. Estradiol Enanthate has been used as an injectable contraceptive.

InChI:InChI=1/C25H36O3/c1-3-4-5-6-7-24(27)28-23-13-12-22-21-10-8-17-16-18(26)9-11-19(17)20(21)14-15-25(22,23)2/h9,11,16,20-23,26H,3-8,10,12-15H2,1-2H3/t20-,21-,22+,23+,25+/m1/s1

Upstream product

• 50-28-2 estradiol 
• 2528-61-2 Heptanoic acid chloride 
• 7732-97-0 3,17-diheptanoic acid-17β-estradiol 
• 434-22-0 19-nortestosterone 
• 122386-52-1 3-benzoyloxy-17β-heptanoyloxy-estra-1,3,5(10)-triene 

Downstream Products

• 50-28-2 estradiol 
• 31299-96-4 estradiol-17β 3-β-D-glucopyranoside 

Relevant articles and documents

Synthetic technology for oestradiol 17-heptanoate

The invention discloses a synthetic technology for oestradiol 17-heptanoate, and further provides a preparation method for the oestradiol 17-heptanoate. The method comprises the following steps that 1, 17beta-estradiol serves as a raw material and reacts with heptanoyl chloride under the catalytic action of pyridine so as to obtain 3.17-diheptylic acid-17beta-estradiol; 2, the 3.17-diheptylic acid-17beta-estradiol in the step 1 serves as a raw material, in an alcohol solvent, hydrolysis reaction is carried out under the action of alkaline, and post-treatment is carried out so as to obtain a crude product of the oestradiol 17-heptanoate; and 3, the crude product of the oestradiol 17-heptanoate in the step 2 serves as a raw material, and refining is carried out by adopting methanol so as toobtain a refined product of the oestradiol 17-heptanoate. The preparation method for the oestradiol 17-heptanoate has the advantages that the technological method is simple, the yield of the target product is high, the production cost is low, the generation amount of chemical pollutants is small, and the method is suitable for industrial production.