49561-47-9 Usage
Structure
A thiazole ring fused to a furan ring with a nitro group attached to the furan ring and a vinyl group attached to the thiazole ring
+ Antimicrobial
The compound has been studied for its ability to inhibit the growth of microorganisms
+ Antitumor
The compound has been studied for its potential to prevent the growth of cancer cells
+ Biological activity
The nitrofuran and thiazole moieties in the compound are known to possess biological activities, making it a potentially significant molecule in medicinal chemistry research.
Check Digit Verification of cas no
The CAS Registry Mumber 49561-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,5,6 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 49561-47:
(7*4)+(6*9)+(5*5)+(4*6)+(3*1)+(2*4)+(1*7)=149
149 % 10 = 9
So 49561-47-9 is a valid CAS Registry Number.
49561-47-9Relevant articles and documents
Chemotherapeutic nitroheterocycles. Antischistosomal properties of nitrofurylvinyl and nitrothienylvinyl heterocycles
Henry,Brown,Cory,et al.
, p. 1287 - 1291 (2007/10/05)
A series of 24 analogs of the experimental antischistosomal agent, 5 amino 3 [2 (5 nitro 2 furyl) vinyl] 1,2,4 oxadiazole, was prepared and evaluated in mice infected with Schistosoma mansoni. Although antischistosomal activity was widespread in the series, only four of the compounds showed significant curative properties. Compounds containing 2 imidazolyl and 2 pyridyl groups gave cure rates around 25% at 400 and 250 mg/kg dose levels, respectively. The 2 thiazolyl and 2 pyrimidyl derivatives were especially notable, yielding 100% cures at 250 and 200 mg/kg dose levels, respectively.
