49572-76-1

Upstream product

• 82-02-0 Khellin 
• 484-51-5 5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran 
• 100-52-7 benzaldehyde 

Downstream Products

• 55008-32-7 2-benzylidene-4,8-dimethoxy-benzo[1,2-b;5,4-b']difuran-3-one 
• 61340-48-5 (4-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-(4,6,7-trimethoxy-benzofuran-5-yl)-methanone 
• 61340-60-1 (3,4-diphenyl-4,5-dihydro-isoxazol-5-yl)-(6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-methanone 
• 1355094-17-5 N-(4,9-dimethoxy-5-styryl-7H-furo[3,2-g]chromen-7-ylidene)benzenamine 
• 1355094-19-7 4,9-dimethoxy-5-styryl-7H-furo[3,2-g]chromen-7-one 
• 92663-31-5 C₃₁H₂₅O₅P 
• 92663-54-2 Phosphoric acid 4,7-dimethoxy-5-[(E)-(3-phenyl-acryloyl)]-benzofuran-6-yl ester diethyl ester 
• 61340-56-5 4,7-dimethoxy-5-(3-phenyl-4,5-dihydro-isoxazol-5-yl)-benzofuran-6-ol 
• 61340-52-1 4,7-dimethoxy-5-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzofuran-6-ol 
• 6430-96-2 5-(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)-4,7-dimethoxy-benzofuran-6-ol 
• 61340-64-5 5-(2-amino-6-phenyl-6H-[1,3]thiazin-4-yl)-4,7-dimethoxy-benzofuran-6-ol 
• 62061-92-1 1-benzyl-6-(6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyridine-3-carboxylic acid benzylamide 
• 102078-28-4 3t-phenyl-1-(4,6,7-trimethoxy-benzofuran-5-yl)-propenone 

Relevant academic research and scientific papers

FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION

The present invention relates to the furanochalcone class of compounds of general formula A. The present invention particularly relates to the synthesis of furanochalcones and their CYP1A1, CYP1A2 and CYP1B1 inhibitory activity. In addition, the invention relates to the prevention or treatment of cancer caused by polyaromatic hydrocarbons (PAHs), 4-nitroquinoline-1-oxide, and N-nitroso-N- methylurea, heterocyclic amines, estrogen and 17β-estradiol, resulting from the inhibition of CYP1A1, CYP1A2 and CYP1B1 enzymes.

Chemistry of phosphorus ylides. Part 34 : Synthesis of chromenone phosphanylidene and cyclobutylidene derivatives

The reaction of nucleophilic phosphacumulene ylides with visnaginone and khellinone afforded the corresponding phosphanylidene and furochromene derivatives. Moreover, pyranochromenes were obtained from the reaction of chromene carbaldehydes with phosphacumulenes. On the other hand, the phosphanylidene-cyclobutylidenes and their dimers were produced from the reaction of furochromene carbaldehydes with the same phosphonium reagents.

Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity

The voltage-gated potassium channel Kv1.3 constitutes a promising new target for the treatment of T-cell-mediated autoimmune diseases such as multiple sclerosis. In this study, we report the discovery of two new classes of Kv1.3 blockers based on the natu

NOVEL CHALCONE DERIVATIVES AND USES THEREOF

Various chalcone derivatives of the general formula (I) are described and the variables, A, B, m and R1 to R10 are as defined in the specification. These derivatives can be useful in the modulation of potassium channel activity in ce