49572-77-2

Upstream product

• 484-51-5 5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran 
• 123-11-5 4-methoxy-benzaldehyde 
• 82-02-0 Khellin 
• 37833-19-5 6-hydroxy-4,7-dimethoxy-5-acetoacetylbenzofuran 
• 52249-80-6 2,4-dihydroxy-3,6-dimethoxybenzaldehyde 
• 52249-81-7 4-benzyloxy-2-hydroxy-3,6-dimethoxybenzaldehyde 
• 42528-81-4 2,6-bis-benzyloxy-benzene-1,4-diol 
• 20032-42-2 2,5-dimethoxyresorcinol 
• 6274-74-4 2,6-dibenzyloxy-1,4-dimethoxybenzene 
• 872285-19-3 5-acetyl-6-hydroxy-4,7-dimethoxy-benzofuran-2-carboxylic acid 
• 854898-32-1 6-benzyloxy-4,7-dimethoxy-benzofuran-2-carboxylic acid ethyl ester 

Downstream Products

• 62061-97-6 4,9-dimethoxy-7-(4-methoxy-phenyl)-6,7-dihydro-furo[3,2-g]chromen-5-one 
• 1443787-85-6 (2E)-1-(6-hydroxy-4,7-dimethoxy-1-benzofuran-5-yl)-3-(4-methoxyphenyl)prop-2-ene-1-thione 
• 61340-49-6 [4-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-(4,6,7-trimethoxy-benzofuran-5-yl)-methanone 
• 61340-61-2 (6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-[4-(4-methoxy-phenyl)-3-phenyl-4,5-dihydro-isoxazol-5-yl]-methanone 
• 61340-65-6 5-[2-amino-6-(4-methoxy-phenyl)-6H-[1,3]thiazin-4-yl]-4,7-dimethoxy-benzofuran-6-ol 
• 61340-53-2 4,7-dimethoxy-5-[5-(4-methoxy-phenyl)-4,5-dihydro-isoxazol-3-yl]-benzofuran-6-ol 
• 61340-57-6 4,7-dimethoxy-5-[3-(4-methoxy-phenyl)-4,5-dihydro-isoxazol-5-yl]-benzofuran-6-ol 
• 1628222-40-1 2-amino-6-(5-hydroxy-4,7-dimethoxy-1-benzofuran-6-yl)-4-(4-methoxyphenyl)nicotinonitrile 
• 1628222-58-1 8-(5-hydroxy-4,7-dimethoxybenzofuran-6-yl)-6-(4-methoxyphenyl)pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5(1H)-thione 
• 1628222-56-9 2-hydrazinyl-7-(5-hydroxy-4,7-dimethoxybenzofuran-6-yl)-5-(4-methoxyphenyl)pyrido[2,3-d]pyrimidine-4(3H)-thione 
• 1628222-54-7 7-(5-hydroxy-4,7-dimethoxybenzofuran-6-yl )-5-(4-methoxyphenyl)-2-(methylthio)[2,3-d]pyrimidine-4(3H)-thione 
• 1628222-48-9 7-(5-hydroxy-4,7-dimethoxybenzofuran-6-yl)-5-(4-methoxyphenyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dithione 
• 1628222-47-8 8-(5-chloro-4,7-dimethoxy-1-benzofuran-6-yl)-10-(4-methoxyphenyl)pyrido[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine-3-thiol 
• 1628222-46-7 8-(5-chloro-4,7-dimethoxy-1-benzofuran-6-yl)-10-(4-methoxyphenyl)-3-methylpyrido[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine 

Relevant academic research and scientific papers

FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION

The present invention relates to the furanochalcone class of compounds of general formula A. The present invention particularly relates to the synthesis of furanochalcones and their CYP1A1, CYP1A2 and CYP1B1 inhibitory activity. In addition, the invention relates to the prevention or treatment of cancer caused by polyaromatic hydrocarbons (PAHs), 4-nitroquinoline-1-oxide, and N-nitroso-N- methylurea, heterocyclic amines, estrogen and 17β-estradiol, resulting from the inhibition of CYP1A1, CYP1A2 and CYP1B1 enzymes.

Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity

The voltage-gated potassium channel Kv1.3 constitutes a promising new target for the treatment of T-cell-mediated autoimmune diseases such as multiple sclerosis. In this study, we report the discovery of two new classes of Kv1.3 blockers based on the natu

Photochemical reaction of phenanthrenequinone with some new aurones derived from khellin and visnagin

Phenanthrenequinone 2 and aurones 5a-h are potentially capable of undergoing an interesting photochemical reaction leading to the formation of the adducts 6a-h. The structures of the 1,4-dioxine derivatives 6a-h were firmly established on the basis of analytical data and spectroscopic evidences.