49580-44-1Relevant academic research and scientific papers
N-N bond formation in Ugi processes: from nitric acid to libraries of nitramines
Mercalli, Valentina,Nyadanu, Aude,Cordier, Marie,Tron, Gian Cesare,Grimaud, Laurence,El Kaim, Laurent
, p. 2118 - 2121 (2017)
The Ugi reaction has drawn considerable attention over the years leading to numerous libraries of heterocycles and various extensions changing the nature of the components of the coupling. We report here the use of nitric acid as carboxylic acids surrogates, displaying the first aminative Ugi-type reaction leading to nitramines.
A Metal-Free and Ionic Liquid-Catalyzed Aerobic Oxidative Bromination in Water
Wang, Jian,Chen, Shu-Bin,Wang, Shu-Guang,Li, Jing-Hua
, p. 513 - 517 (2015/03/30)
A metal-free aerobic oxidative bromination of aromatic compounds in water has been developed. Hydrobromic acid is used as a bromine source and 2-methylpyridinium nitrate ionic liquid is used as a recyclable catalyst. Water is used as the reaction mediate. This is the first report of aerobic oxidative bromination using only catalytic amount of metal-free catalyst. This system shows not only high bromine atom economy, but also high bromination selectivity. The possible mechanism and the role of the catalyst in this system have also been discussed.
