496018-41-8Relevant academic research and scientific papers
Linear polynuclear tetrazole-containing compounds
Morozova,Komissarov,Esikov,Zubarev,Malin,Ostrovskii
, p. 1532 - 1538 (2007/10/03)
Linear polynuclear tetrazole-containing compounds were synthesized. Alkylation of 5-[ω-(5-phenyl-2-tetrazolyl)alkyl]tetrazoles with ethyl bromoacetate and chloroacetamide gave the corresponding esters and amides. Treatment of the latter with tetrachlorosilane-sodium azide afforded compounds containing three tetrazole rings linked through polymethylene bridges. Acid ionization constants of the products possessing an NH-tetrazole ring (pK a = 2.9-3.2) and the corresponding carboxylic acids (pK a = 2.9-3.1) in aqueous methanol were determined by potentiometric titration.
