49604-29-7

Basic information

• Product Name: 1,3-Dioxolo[4,5-g]quinazoline-6(5H)-thione, 7,8-dihydro-5-(1-methylethyl)-8-phenyl-
• CAS NO: 49604-29-7
• Molecular Formula: C18H18N2O2S
• Molecular Weight: 326.419
• Mol File: 49604-29-7.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolo[4,5-g]quinazoline-6(5H)-thione, 7,8-dihydro-5-(1-methylethyl)-8-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolo[4,5-g]quinazoline-6(5H)-thione, 7,8-dihydro-5-(1-methylethyl)-8-phenyl-(49604-29-7)
• EPA Substance Registry System: 1,3-Dioxolo[4,5-g]quinazoline-6(5H)-thione, 7,8-dihydro-5-(1-methylethyl)-8-phenyl-(49604-29-7)

Safety Data

• Hazardous Substances Data: 49604-29-7(Hazardous Substances Data)

Upstream product

• 60889-61-4 2-isopropylamino-4,5-methylenedioxybenzhydrol 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 49604-27-5 N¹-isopropyl-N¹-(3,4-methylenedioxyphenyl)-N³-benzoylthiourea 
• 10368-14-6 N-isopropyl-3,4-(methylenedioxy)aniline 
• 49604-28-6 N-isopropyl-N-<3,4-(methylenedioxy)phenyl>thiourea 
• 100-52-7 benzaldehyde 

Downstream Products

• 49604-30-0 1-isopropyl-6,7-methylenedioxy-4-phenylquinazolin-2(1H)-thione 

Relevant articles and documents

Antiinflammatory Properties of 8-Aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones

A series of 8-aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones was prepared and evaluated for antiinflammatory activity.The 8-phenyl-, 8-(3-fluorophenyl)-, and 8-(4-fluorophenyl)-2H-1,3-dioxoloquinazolin-6(5H)-ones and the 8-phenyl-2H-1,3-dioxoloquinazolin-6(5H)-thione were found to exhibit activity in the range of indomethacin and proquazone.

2-(N-thiocarbamoyl-n-substituted-amino)-3,4-methylenedioxy benzhydrols

1,4 disubstituted-methylenedioxy-quinazoline-2(1H)-thiones are provided which are useful as pharmaceutical agents, e.g. anti-inflammatory agents. The title compounds are intermediates in their preparation.