496050-92-1Relevant academic research and scientific papers
Enantioselective synthesis of a highly preorganised 2′-deoxy-spiro-nucleoside
Wendeborn, Sebastian,Binot, Gregory,Nina, Mafalda,Winkler, Tammo
, p. 1683 - 1687 (2002)
The synthesis of a novel spiro-nucleotide, in which the C(4′) and the C(5′) of a nucleotide are connected by an additional ethylene bridge, is reported. The γ-torsional angle of the resulting novel nucleotides is in the region of the one observed in natural double stranded DNA.
