496050-96-5

Upstream product

• 3839-31-4 dimethyl(phenyl)silyllithium 
• 496050-90-9 (5S,6S)-6-Triethylsilanyloxy-1-oxa-spiro[4.4]non-3-en-2-one 
• 496050-92-1 (5R,6S)-6-Hydroxy-4-phenylsulfanyl-1-oxa-spiro[4.4]nonan-2-one 
• 994-30-9 triethylsilyl chloride 

Relevant academic research and scientific papers

Enantioselective synthesis of a highly preorganised 2′-deoxy-spiro-nucleoside

The synthesis of a novel spiro-nucleotide, in which the C(4′) and the C(5′) of a nucleotide are connected by an additional ethylene bridge, is reported. The γ-torsional angle of the resulting novel nucleotides is in the region of the one observed in natural double stranded DNA.