496054-83-2Relevant academic research and scientific papers
Synthesis, evaluation and metabolic studies of radiotracers containing a 4-(4-[18F]-fluorobenzyl)piperidin-1-yl moiety for the PET imaging of NR2B NMDA receptors
Labas, Romain,Gilbert, Gwéna?lle,Nicole, Olivier,Dhilly, Martine,Abbas, Ahmed,Tirel, Olivier,Buisson, Alain,Henry, Jo?l,Barré, Louisa,Debruyne, Danièle,Sobrio, Franck
, p. 2295 - 2309 (2011/06/21)
In this study, novel specific PET radioligands containing the 4-(4-fluorobenzyl)piperidine moiety and selectively antagonistic for the NR2B subunit containing NMDA receptors were developed. Two antagonists, RGH-896 (1a) and 4-(4-fluorobenzyl)piperidinyl-1
