49612-06-8 Usage
Uses
Used in Pharmaceutical Synthesis:
2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
As a member of the aminoquinoline class, 2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is utilized in chemical research to explore its properties and potential reactions. This helps in understanding its behavior and further enhances its applications in various fields.
Used in Antiviral Applications:
2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is used as an antiviral agent, leveraging its potential biological activities to combat viral infections. Its antiviral properties are being studied for possible use in the development of treatments for various viral diseases.
Used in Anticancer Applications:
2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is also used as an anticancer agent, where its potential biological activities are harnessed to target and inhibit the growth of cancer cells. Research is ongoing to determine its effectiveness and possible integration into cancer treatment protocols.
Used in Antibacterial Applications:
2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is used in antibacterial applications, where its properties are employed to fight against bacterial infections. Its potential to inhibit bacterial growth is being explored for use in the development of new antibiotics.
Used in Analytical Chemistry as a Fluorescent Probe:
In the field of analytical chemistry, 2,8-DIMETHYL-4-HYDRAZINOQUINOLINE is used as a fluorescent probe for detecting and quantifying various substances in biological samples. Its fluorescent properties allow for sensitive and selective detection, making it a valuable tool in research and diagnostics.
Check Digit Verification of cas no
The CAS Registry Mumber 49612-06-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,6,1 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 49612-06:
(7*4)+(6*9)+(5*6)+(4*1)+(3*2)+(2*0)+(1*6)=128
128 % 10 = 8
So 49612-06-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3/c1-7-4-3-5-9-10(14-12)6-8(2)13-11(7)9/h3-6H,12H2,1-2H3,(H,13,14)
49612-06-8Relevant academic research and scientific papers
N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors
Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang
, p. 3073 - 3079,7 (2020/08/20)
A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.
Synthesis and some transformations of 6(8)-substituted 4-hydrazino-2- methylquinolines
Avetisyan,Aleksanyan,Ambartsumyan
experimental part, p. 427 - 431 (2010/09/20)
6(8)-Substituted 4-hydrazino-2-methylquinolines were synthesized by reaction of the corresponding 4-chloro-2-methylquinolines with hydrazine hydrate. Reactions of the title compounds with ethyl acetoacetate and acetone gave 2,4-dimethyl-1H-pyrrolo[3,2-c]q
