49639-34-1Relevant academic research and scientific papers
One-Pot Sequential Multistep Transformation of α,β-Unsaturated Trifluoromethyl Ketones: Facile Synthesis of Trifluoromethylated 2-Pyridones
Lv, Ning,Tian, Yi-Qiang,Zhang, Fa-Guang,Ma, Jun-An
supporting information, p. 605 - 609 (2019/03/07)
A one-pot transformation of α,β-unsaturated trifluoromethyl ketones with 2-(phenylsulfinyl)acetamide to give trifluoromethylated 2-pyridones is realized. The reaction proceeds under mild conditions and involves multiple steps in an expeditious and controlled sequence to provide efficient access to a broad range of trifluoromethylated 2-pyridones in moderate to high yields. Moreover, further synthetic manipulations permit the routine synthesis of a diverse array of trifluoromethylated pyridines with good efficiency.
2-pyridone synthesis using 2-(phenylsulfinyl)acetamide
Fujii, Masaya,Nishimura, Takuya,Koshiba, Takahiro,Yokoshima, Satoshi,Fukuyama, Tohru
supporting information, p. 232 - 234 (2013/04/10)
2-Pyridones were prepared by means of an efficient protocol including the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination.
EFFECT OF MOLECULAR STRUCTURE ON OPTICAL PROPERTIES OF SULFOXIDE SYSTEMS. PHENYL- AND m-BROMOPHENYLSULFINYLACETIC ACIDS AND SOME OF THEIR DERIVATIVES. PART I
Janczewski, Marian,Najda, Teresa,Jablonska-Pikus, Teresa
, p. 1297 - 1312 (2007/10/02)
The synthesis of phenylsulfinyl- and sulfonyl-acetic acids and their m-bromo derivatives is described.The racemic sulfoxides were resolved into enantiomers.The absolute configurations of enantiomers were elucitated.The optical rotatory dispersion of laevorotatory enantiomers, their amides, p-nitrobenzyl and p-bromophenacyl esters was determined.
