49641-01-2

Upstream product

• 108054-54-2 diethyl (4-chlorophenyl)(hydroxy)methylphosphonate 
• 108-24-7 acetic anhydride 
• 104-88-1 4-chlorobenzaldehyde 
• 64-17-5 ethanol 
• 773144-66-4 acetic acid (4-chloro-phenyl)-ethoxyphosphinoyl-methyl ester 
• 75-36-5 acetyl chloride 

Relevant academic research and scientific papers

Copper Triflate as a Useful Catalyst for the High-Yielding Preparation of α-Acetyloxyphosphonates under Solvent-Free Conditions

A high-yielding and convenient procedure for the efficient conversion of α-hydroxyphosphonates to α-acetyloxyphosphonates using acetic anhydride in the presence of catalytic amounts of copper triflate is described.

Enantioselective acylphosphonylation-dual lewis acid-lewis base activation of aldehyde and acylphosphonate

Acetoxyphosphonates were obtained by a one-step procedure consisting of reaction of diethyl acetylphosphonate with prochiral aldehydes in the presence of a catalytic system comprising a chiral Lewis acid, an achiral Lewis base, and a Br?nstedt base. Best

Preparation and characterization of multi-walled carbon nanotubes (MWCNTs), functionalized with phosphonic acid (MWCNTs-C-PO3H2) and its application as a novel, efficient, heterogeneous, highly selective and reusable catalyst for acetylation of alcohols, phenols, aromatic amines, and thiols

A novel, efficient, heterogeneous, and reusable multi-walled carbon nanotubes (MWCNTs), functionalized with phosphonic acid (MWCNTs-C-PO 3H2) has been synthesized. The synthesized CNTs were characterized using some electron microscopic techniques such as scanning electron microscopy (SEM), atomic force microscopy (AFM), Energy dispersive X-ray spectroscopy (EDAX), and also some thermal and spectroscopic methods such as thermogravimetry (TG). The nitrogen adsorption behavior of the MWCNTs-C-PO3H2 catalyst was evaluated using the TG instrumentation system at 25°C. The catalyst was applied successfully for highly efficient and selective acetylation of alcohols, phenols, thiols and aromatic amines with acetic anhydride at room temperature under solvent-free conditions. The reusability of the catalyst was checked and the recovered catalyst was reused for five runs without significant loss in activity.

Stereospecific transformation of protected Pa-H group into Pa-O or Pa-N group in one-pot reaction

A general and efficient procedure for converting 1,1- diethoxyalkylphosphinates into phosphonates or phosphonamides is described by the application of bromine with moderate to high yields and good purity in a one-pot reaction. H-Phosphinate reacts stereospecifically with bromine and subsequently couples with nucleophile to form the corresponding optically active R1P(O)(OEt)X with retention of configuration at the phosphorus center. For α-amino-H-phosphinates, the transformation could be realized without the protection of the amino group.

Iron-doped single-walled carbon nanotubes as new heterogeneous and highly efficient catalyst for acylation of alcohols, phenols, carboxylic acids and amines under solvent-free conditions

Iron-doped single-walled carbon nanotubes (Fe/SWCNTs) represent an efficient and new heterogeneous reusable catalyst for the acylation of a variety of alcohols, phenols, carboxylic acids and amines with acid chlorides or acid anhydrides under solvent-free conditions. The reactions of various primary, secondary, tertiary, and benzylic alcohols, diols, phenols, as well as aromatic and aliphatic amines give acylated adducts in good to excellent yields.

Facile and high-yielding preparation of α-acetoxyphosphonates from α-hydroxyphosphonates assisted by microwave irradiation

A convenient and eco-friendly procedure is described for the efficient preparation of a variety of α-acetyloxyphosphonates from their corresponding α-hydroxyphosphonates using acetic anhydride under microwave irradiation in the absence of solvent.