496786-98-2

Basic information

• Product Name: 4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: TERT-BUTYL 4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-2-PYRIDINYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE;TERT-BUTYL 4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE-1-CARBOXYLATE;6-(4-TERT-BUTOXYCARBONYLPIPERAZINYL)PYRIDINE-3-BORONIC ACID, PINACOL ESTER;4-(5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL)-1-BOC-PIPERAZINE;4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;2-(4-BOC-PIPERAZINE)PYRIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-BOC-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-TERT-BUTOXYCARBONYLPIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID, PINACOL ESTER
• CAS NO: 496786-98-2
• Molecular Formula: C₂₀H₃₂BN₃O₄
• Molecular Weight: 389.3
• Product Categories: Heterocyclic Compounds;Boronic ester;Organoborons;Pyridine
• Mol File: 496786-98-2.mol
• Article Data: 11

Chemical Properties

• Melting Point: 165-169 °C
• Boiling Point: 515.9 °C at 760 mmHg
• Flash Point: 265.8 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 9.48E-11mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 8.41±0.31(Predicted)
• CAS DataBase Reference: 4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(496786-98-2)
• EPA Substance Registry System: 4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(496786-98-2)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 496786-98-2(Hazardous Substances Data)

Usage

Uses

6-(4-Boc-piperazin-1-yl)pyridine-3-boronic Acid Pinacol Ester is used as a reactant in the preparation of fluorogenic probes used to distinguish chemical warfare agents and their mimics.

InChI:InChI=1/C20H32BN3O4/c1-18(2,3)26-17(25)24-12-10-23(11-13-24)16-9-8-15(14-22-16)21-27-19(4,5)20(6,7)28-21/h8-9,14H,10-13H2,1-7H3

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 153747-97-8 5-Bromo-2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 25240-59-9 pinacolboronic acid 
• 766-11-0 5-bromo-2-fluoropyridine 
• 53939-30-3 5-bromo-2-chloropyridine 
• 73406-97-0 5-bromo-2-(piperazin-1-yl)pyridine 

Downstream Products

• 1323919-74-9 4-{5'-[2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[3,3']bipyridinyl-6-yl}-piperazine-1-carboxylic acid tert-butyl ester 
• 1383481-17-1 tert-butyl 4-(5-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}pyridin-2-yl)piperazine-1-carboxylate 
• 1379522-33-4 tert-butyl 4-(5-{[4-(methylsulfonyl)benzyl]oxy}pyridin-2-yl)piperazine-1-carboxylate 
• 1419063-03-8 tert-butyl 4-(5-(4-(1-(2-cyano-1,2-dimethylhydrazinyl)-4-methyl-1-oxopentan-2-ylcarbamoyl)phenyl)pyridin-2-yl)piperazine-1-carboxylate 
• 1419063-02-7 tert-butyl 4-(5-(3-(1-(2-cyano-1,2-dimethylhydrazinyl)-4-methyl-1-oxopentan-2-ylcarbamoyl)phenyl)pyridin-2-yl)piperazine-1-carboxylate 
• 1431703-21-7 C₃₉H₅₄N₆O₅Si 
• 1654738-73-4 C₄₁H₄₈F₂N₈O₅ 
• 1613643-22-3 C₃₁H₃₂F₂N₈O 
• 1613643-71-2 C₂₀H₂₅FN₄O₂ 
• 1616289-66-7 tert-butyl 4-{5-[2-{[2-(benzyloxy)-4,6-dimethylpyridin-3-yl]methyl}-8-chloro-1-oxo-7-(propan-2-yloxy)-1,2,3,4-tetrahydroisoquinolin-5-yl]pyridin-2-yl}piperazine-1-carboxylate 

Relevant articles and documents

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