496789-49-2

Upstream product

• 496789-57-2 C₃₈H₃₇BrN₄O₁₀ 
• 496789-54-9 2-benzyloxycarbonylamino-3-(3-{3-[4-benzyloxymethyl-2-(1-tert-butoxycarbonylamino-2-methyl-propyl)-oxazol-5-yl]-7-bromo-1-methoxymethyl-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-methoxymethoxy-phenyl)-propionic acid 
• 496789-45-8 2-benzyloxycarbonylamino-3-(3-{3-[4-benzyloxymethyl-2-(1-tert-butoxycarbonylamino-2-methyl-propyl)-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-propionic acid methyl ester 
• 496789-47-0 C₄₄H₄₅BrN₄O₉ 
• 793728-01-5 C₄₂H₄₁BrN₄O₈ 
• 496789-44-7 (S)-3-(3-{3-[2-((S)-1-Amino-2-methyl-propyl)-4-benzyloxymethyl-oxazol-5-yl]-7-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl}-4-hydroxy-phenyl)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 496789-56-1 C₃₈H₃₉BrN₄O₉ 
• 793728-21-9 C₃₈H₃₇BrN₄O₉ 
• 496789-48-1 C₃₃H₃₁BrN₄O₇ 
• 793727-79-4 {1-[4-benzyloxymethyl-5-(7-bromo-3-hydroxy-1-methoxymethyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-oxazol-2-yl]-2-methyl-propyl}-carbamic acid tert-butyl ester 
• 496789-39-0 (S)-2-(1-tert-butoxycarbonylamino-2-methyl)propyloxazole-4-methanol benzyl ether 
• 496789-53-8 (S)-2-(1-tert-butoxycarbonylamino-2-methyl)propyloxazole-4-methanol 
• 158068-94-1 (S)-2-((S)-1-((tert-butoxycarbonyl)amino)-2-methylpropyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 71017-98-6 methyl (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-3-hydroxypropanoate 

Downstream Products

• 496789-50-5 C₄₈H₄₂N₆O₉ 
• 496789-58-3 C₄₈H₄₃BrN₆O₉ 

Relevant academic research and scientific papers

Chemistry and biology of diazonamide A: First total synthesis and confirmation of the true structure

With the addition of a tenth ring, the exchange of an oxygen atom for a nitrogen in the heart of the molecule, and a different terminal residue, the revised architecture for diazonamide A (1) provided an even more challenging molecular puzzle for chemical synthesis than its predecessor. In this article, we detail the first successful total synthesis of diazonamide A, an endeavor which not only verified its proper connectivities and established the stereochemistry of its previously unassignable C-37 chiral center, but which also was attended by the development of several new synthetic strategies and tactics.