49681-94-9 Usage
Uses
Used in Organic Synthesis:
6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one is used as a reagent in organic synthesis for its ability to facilitate the synthesis of heterocyclic compounds and pharmaceuticals. Its unique structure allows for versatile reactions and the formation of a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one is used as a key intermediate in the development of various drugs. Its potential biological activities, including antioxidant and anticancer properties, make it a promising candidate for the creation of novel therapeutic agents.
Used in Chemical Research:
6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one is used as a valuable tool in chemical research for its ability to trap and stabilize reactive intermediates in chemical reactions. This property aids researchers in understanding and elucidating reaction mechanisms, which is crucial for the advancement of chemical knowledge and the development of new synthetic methods.
Used in Antioxidant Applications:
6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one is used as an antioxidant agent due to its potential biological activity. Its ability to neutralize reactive oxygen species and protect cells from oxidative damage makes it a candidate for use in various applications, such as in the development of nutraceuticals and cosmeceuticals.
Used in Anticancer Research:
In anticancer research, 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one is used for its potential anticancer properties. Its ability to target and inhibit the growth of cancer cells makes it a subject of interest for the development of new cancer therapies and the improvement of existing treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 49681-94-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,6,8 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 49681-94:
(7*4)+(6*9)+(5*6)+(4*8)+(3*1)+(2*9)+(1*4)=169
169 % 10 = 9
So 49681-94-9 is a valid CAS Registry Number.
49681-94-9Relevant academic research and scientific papers
Investigation into a By-product from the Reaction of 2-Amino-5-methylbenzoic Acid with Ammonium Thiocyanate
Kennewell, Peter D.,Scrowston, Richard M.,Shenouda, Ibrahim G.,Tully, W. Roger,Westwood, Robert
, p. 2001 - 2025 (2007/10/02)
One of the by-products from the reaction of 2-amino-5-methylbenzoic acid with ammonium thiocyanate is shown to be 2,3-dihydro-5-methyl-2-thioxo-3-p-tolylquinazolin-4(1H)-one (6).This reacts with hydrazine to give three products (21)-(23), which have been converted into tetrazolo- (27) and 1,2,4-triazolo-quinazolino-derivatives (20) and (30).The products from the reaction of o-aminoacetophenone with an aryl isothiocyanate are converted into a reactive 1-azabuta-1,3-diene intermediate (34), which undergoes a ? cycloaddition reaction with dimethyl acetylenedicarboxylate, followed by a retro-Diels-Alder reaction, to give dimethyl 4-methylquinoline-2,3-dicarboxylate.