6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
CAS No.:49681-94-9
Molecular Formula:C9H8N2OS
Molecular Weight:192.241
Hs Code.:
DSSTox Substance ID:DTXSID10509352
Nikkaji Number:J354.150I
Wikidata:Q82366838
Mol file:49681-94-9.mol

Synonyms:6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one;49681-94-9;6-methyl-2-sulfanylidene-1H-quinazolin-4-one;6-methyl-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one;SCHEMBL1396346;SCHEMBL11261496;6-methyl-2-thioxo-4-quinazolone;DTXSID10509352;UPJOIVAFYDFKND-UHFFFAOYSA-N;2-mercapto-6-methylquinazolin-4-ol;NSC818010;NSC-818010;FT-0740273;6-Methyl-2-sulfanylidene-2,3-dihydroquinazolin-4(1H)-one

Suppliers and Price of 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

Chemical Property:

PSA：84.81000
LogP:1.93250
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:192.03573406
Heavy Atom Count:13
Complexity:254

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)NC(=S)NC2=O

Technology Process of 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

There total 2 articles about 6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 2941-78-8
2-Amino-5-methylbenzoic acid

: 1147550-11-5
ammonium thiocyanate

: 49681-94-9
6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydrochinazolin

: 622-52-6
p-methylphenylthiourea

: 106020-08-0
2,3-dihydro-6-methyl-2-thioxo-3-p-tolylquinazolin-4(1H)-one

: 621-01-2
N,N'-Bis(p-tolyl)thiourea

Guidance literature:: In diethylene glycol; at 150 ℃; for 2h;

Reference yield: 9.0%

: 2941-78-8
2-Amino-5-methylbenzoic acid

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 49681-94-9
6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydrochinazolin

: 19181-53-4
6-Methyl-quinazolin-4-one

Guidance literature:: With sulfur; at 200 - 210 ℃; for 0.333333h;
DOI:10.1007/BF00515086

Reference yield: 90.0%

: 49681-94-9
6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydrochinazolin

: 74-88-4
methyl iodide

: 174313-65-6
2-(methylsulfanyl)-6-bromo-quinazolin-4(3H)-one

Guidance literature:: 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydrochinazolin; With sodium methylate; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

methyl iodide; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 22h;