49691-65-8 Usage
Uses
Used in Pharmaceutical Industry:
N'-[[(2-benzoyl-4-chlorophenyl)(chloroacetyl)amino]methylene]chloroacetohydrazide is used as an intermediate compound in the synthesis of various pharmaceuticals for its potential anticonvulsant properties. Its weaker anticonvulsant effect compared to Diazepam makes it a valuable candidate for further research and development in the creation of new drugs with improved efficacy and reduced side effects.
Used in Research and Development:
In the field of scientific research, N'-[[(2-benzoyl-4-chlorophenyl)(chloroacetyl)amino]methylene]chloroacetohydrazide serves as a key compound for studying the structure-activity relationship of anticonvulsant drugs. Its unique structure allows researchers to explore the effects of different functional groups on the compound's biological activity, potentially leading to the discovery of more effective anticonvulsant agents.
Used in Drug Metabolism Studies:
As a metabolite of Diazepam, N'-[[(2-benzoyl-4-chlorophenyl)(chloroacetyl)amino]methylene]chloroacetohydrazide is also used in drug metabolism studies to understand the metabolic pathways and pharmacokinetics of Diazepam and its related compounds. This information can be crucial in optimizing drug dosages, minimizing side effects, and improving patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 49691-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,6,9 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 49691-65:
(7*4)+(6*9)+(5*6)+(4*9)+(3*1)+(2*6)+(1*5)=168
168 % 10 = 8
So 49691-65-8 is a valid CAS Registry Number.
49691-65-8Relevant academic research and scientific papers
Preparation method of 5-chloro-2-(3-chloromethyl-s-triazolyl)benzophenone hydrochloride
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Paragraph 0011-0012, (2018/04/03)
The invention provides a preparation method of 5-chloro-2-(3-chloromethyl-s-triazolyl)benzophenone hydrochloride. The preparation method comprises the following steps: after uniformly stirring 6-chloro-3-amino-3,4-dihydro-4-hydroxyl-4-phenylquinazoline with a water solution of sodium carbonate in an inert solvent, adding chloroacetyl chloride and carrying out dichloroacetylation reaction; after finishing heat preservation of the dichloroacetylation reaction, adding halogenated hydrocarbon and uniformly stirring; then removing lower-layer saline water and washing with water until the solution is neutral; carrying out distillation to remove the halogenated hydrocarbon; adding glacial acetic acid and carrying out rearrangement reaction; after finishing rearrangement heat-preservation reaction, adding water and carrying out water washing until the solution is neutral; adding hydrochloric acid and carrying out salt formation reaction; centrifuging and drying to obtain the 5-chloro-2-(3-chloromethyl-s-triazolyl)benzophenone hydrochloride. According to the method provided by the invention, high-toxin dichloroethane and pure benzene are eliminated, and an intermediate product does not needto be separated; a preparation technology is simplified, the production cost is reduced, and the preparation method is suitable for industrial production.
