496929-80-7

Basic information

• Product Name: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-(3-methoxyphenyl)-3-(2-propenyl)-
• CAS NO: 496929-80-7
• Molecular Formula: C13H13N3O4
• Molecular Weight: 275.264
• Mol File: 496929-80-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-(3-methoxyphenyl)-3-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-(3-methoxyphenyl)-3-(2-propenyl)-(496929-80-7)
• EPA Substance Registry System: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-(3-methoxyphenyl)-3-(2-propenyl)-(496929-80-7)

Safety Data

• Hazardous Substances Data: 496929-80-7(Hazardous Substances Data)

Upstream product

• 19617-43-7 ethoxycarbonylisocyanate 
• 1017354-64-1 1-allyl-3-(m-anisyl)urea 

Downstream Products

• 847686-66-2 [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde 
• 496929-81-8 1-allyl-3-(3-methoxyphenyl)-5-(2,6-difluorobenzyl)isocyanurate 

Relevant articles and documents

A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists

A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from readily available alkyl- or aryl-isocyanates, primary amines and N-chlorocarbonyl isocyanate in excellent yields. Subsequent alkylation with N-protected amino alcohols afforded the desired 1,3,5-triazine-2,4,6-triones in good yields. This methodology was applied to the synthesis of a chemical library acting as antagonists of the hGnRH receptor.