847686-66-2

Basic information

• Product Name: [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde
• Synonyms: [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde
• CAS NO: 847686-66-2
• Molecular Weight: 403.342
• Mol File: 847686-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde(847686-66-2)
• EPA Substance Registry System: [3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-2,4,6-trioxo-[1,3,5]triazinan-1-yl]-acetaldehyde(847686-66-2)

Safety Data

• Hazardous Substances Data: 847686-66-2(Hazardous Substances Data)

Upstream product

• 496929-80-7 1-allyl-3-(3-methoxyphenyl)isocyanurate 
• 496929-81-8 1-allyl-3-(3-methoxyphenyl)-5-(2,6-difluorobenzyl)isocyanurate 

Relevant articles and documents

A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists

A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from readily available alkyl- or aryl-isocyanates, primary amines and N-chlorocarbonyl isocyanate in excellent yields. Subsequent alkylation with N-protected amino alcohols afforded the desired 1,3,5-triazine-2,4,6-triones in good yields. This methodology was applied to the synthesis of a chemical library acting as antagonists of the hGnRH receptor.