496946-78-2

Usage

Uses

Used in Pharmaceutical Industry:
5-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID is used as a precursor in the synthesis of various pharmaceuticals for its ability to modify and improve the biological activity of drug candidates. Its unique molecular structure allows for the creation of new chemical entities with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 5-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID is utilized in the development of new chemical entities aimed at enhancing crop protection and improving agricultural productivity. Its role as a building block in the synthesis of agrochemicals allows for the exploration of innovative solutions to pest and disease control in crops.

InChI:InChI=1/C10H6F3NO2/c11-10(12,13)6-1-2-7-5(3-6)4-8(14-7)9(15)16/h1-4,14H,(H,15,16)

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 127-17-3 2-oxo-propionic acid 
• 163444-17-5 2-iodo-4-(trifluoromethyl)aniline 

Downstream Products

• 1362860-89-6 methyl-5-trifluoromethyl-1H-indole-2-carboxylate 
• 1373438-75-5 5-bromo-2-hydroxy-N'-{(1E)-1-[5-(trifluoromethyl)-1H-indol-2-yl]ethylidene}benzohydrazide 
• 1228694-04-9 methyl (S)-5-(benzyloxy)-1-(chloromethyl)-3-(5-trifluoromethylindole-2-carbonyl)-1,2-dihydropyrrolo[3,2-e]indole-2-carboxylate 

Relevant academic research and scientific papers

THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION

Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.

METHOD FOR PROMOTING PLANT GROWTH

The present invention provides a method for promoting plant growth, which comprises treating a plant with at least one compound represented by the following Formula (1) The compounds indicated by formula (1) are used to promote the growth of plants. A pla

NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis,

Synthesis and evaluation of a series of C5′-substituted duocarmycin SA analogs

The synthesis and evaluation of a key series of analogs of duocarmycin SA, bearing a single substituent at the C5′ position of the DNA binding subunit, are described.

Acyl indoles, compositions containing such compounds and methods of use

The present invention relates to substituted indoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus and related conditions.

Novel 3,4-Dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a

The preparation of a series of substituted indoles coupled to six- and seven-membered cyclic lactams is described and their role as human glycogen phosphorylase a inhibitors discussed. The SAR of the indole moiety and lactam ring are presented.