496962-20-0Relevant academic research and scientific papers
One-pot synthesis of α-bromoesters and ketones from β-ketoesters and diketones using supported reagents system
Aoyama, Tadashi,Takido, Toshio,Kodomari, Mitsuo
, p. 1873 - 1876 (2007/10/03)
A simple and efficient method has been developed for the synthesis of α-bromoesters and ketones from β-ketoesters and diketones in one pot using a supported reagents system, CuBr2/Al2O 3-Na2CO3/Al2O3, in which β-ketoester reacts first with CuBr2/Al2O3 and the product, α-bromo-β-ketoester, reacts with Na 2CO3/Al2O3 to give the final product, α-bromoesters in good yields.
Synthesis of optically pure (S)-2-acetylthio-3-benzenepropanoic acid via enzymatic resolution
Zhu, Jingyang,You, Li,Zhao, Shannon X,White, Brenda,Chen, Jason G,Skonezny, Paul M
, p. 7585 - 7587 (2007/10/03)
A method of synthesizing optically pure (S)-2-acetylthio-3-benzenepropanoic acid has been developed and good to excellent enantiomeric excess achieved via enzymatic resolution.
