497082-76-5Relevant academic research and scientific papers
Synthesis and biological activities of 4-oxo thiazolidine derivatives
Sanghani,Sanja,Rajani,Godhani
scheme or table, p. 557 - 560 (2009/08/07)
A series of 4-oxo-2-phenyl-thiazolidin-3-yl derivatives 5a-l have been obtained by cyclisation of various Schiff's base 4 with thioglycolic acid. The Schiff's base 4 are obtained by the reaction of appropriate carbonyl compound with (4-oxo-3-p-tolyl-3,4-dihydro-quinazolin-2-yl-sulfanyl)-acetic acid hydrazide 3. The product is characterized by spectral and analytical data. Most of the tested compounds show promising antibacterial and antifungal activity.
