497147-93-0

Usage

General Description

5-Cyano-3-pyridinyl boronic acid is a chemical compound that is used as a reagent in organic synthesis and medicinal chemistry. It consists of a pyridine ring with a cyano group and a boronic acid functional group attached. 5-CYANO-3-PYRIDINYL BORONIC ACID is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its ability to form stable complexes with different metal ions. Additionally, it can be used as a building block in the preparation of various heterocyclic compounds, making it a versatile tool for chemical research and drug development.

InChI:InChI=1/C6H5BN2O2/c8-2-5-1-6(7(10)11)4-9-3-5/h1,3-4,10-11H

Upstream product

• 35590-37-5 5-bromopyridine-3-carbonitrile 
• 5419-55-6 Triisopropyl borate 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1383846-90-9 5-(3-(3-Amino-4-fluoro-1-(1-methyl-6-oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-yl)-1H-isoindol-1-yl)phenyl)nicotinonitrile 
• 1383846-97-6 5-(3-(3-amino-1-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-4-fluoro-1H-isoindol-1-yl)phenyl)nicotinonitrile 
• 1581258-00-5 5-(6-(2-(2,2-dimethyl-4-phenyltetrahydro-2H-pyran-4-yl)ethylamino)pyrazin-2-yl)nicotinonitrile 
• 1416000-35-5 5-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-3-cyanopyridine 
• 1260432-41-4 5-(3-(4-amino-2-(4-(difluoromethoxy)-3,5-dimethylphenyl)-5-methyl-2H-imidazol-2-yl)phenyl)nicotinonitrile 
• 1232333-03-7 3-[2-[1-(hydroxymethyl)cyclopropyl]-8-methoxy[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile 
• 929561-01-3 5-[2-[3-(trifluoromethyl)anilino]thiazol-4-yl]pyridine-3-carbonitrile 

Relevant academic research and scientific papers

ORGANIC COMPOUND AND LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY DEVICE USING THE SAME

The present invention relates to an organic compound having excellent hole injection properties and charge generation properties by substituting an electron withdrawing group (Electron acceptor) for a conjugated bipyridine derivative core, to a light-emitting diode applying the organic compound to at least one organic layer, and to a display device.COPYRIGHT KIPO 2017

HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia ( T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

2-AMINOPYRIMIDIN-4-ONES AND THEIR USE FOR TREATING OR PREVENTING Aβ-RELATED PATHOLOGIES

This invention relates to novel compounds having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy] and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds prov