929561-01-3

Upstream product

• 135450-74-7 5-acetylpyridine-3-carbonitrile 
• 98-16-8 3-trifluoromethylaniline 
• 1736-70-5 3-trifluoromethylphenylthiourea 
• 1840-19-3 1-isothiocyanato-3-trifluoromethyl-benzene 
• 35590-37-5 5-bromopyridine-3-carbonitrile 
• 497147-93-0 3-cyanopyridine-5-boronic acid 

Relevant academic research and scientific papers

4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

4-phenyl-N-(phenyl)thiazol-2-amine and 4-(pyridin-3-yl)-N-( phenyl) thiazol-2-amine derivatives and the corresponding thiadiazole, thiophene, oxazole, oxadiazole, imidazole and triazole derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders.

2-ANILINE-4-ARYL SUBSTITUTED THIAZOLE DERIVATIVES

This invention concerns the use of a compound of formula (I) a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein Z is hydrogen, halo, C1-6alkyl, Het1, HO—C