49715-41-5Relevant academic research and scientific papers
STUDIES ON TETRAHYDROISOQUINOLINES. XIX. SYNTHESIS OF (+/-)-ISOTHEBAINE, (+/-)-1-HYDROXY-2,9-DIMETHOXY-, (+/-)-1-HYDROXY-2,10-DIMETHOXY-, AND (+/-)-2,10-DIMETHOXY-APORPHINES,(+/-)-2,6-DIMETHOXYHOMOMORPHINANDIENONE, AND (+/-)-1-HYDROXY-2,10-DIMETHOXYHOMOAP
Hara, Hiroshi,Hoshino, Osamu,Ishige, Tetsuo,Umezawa, Bunsuke
, p. 1083 - 1087 (2007/10/02)
The title alkaloids and two related aporphines have been prepared in considerable yields by trifluoroacetic acid treatment of the corresponding p-quinol acetates.Keywords: oxidation; lead tetraacetate; p-quinol acetate; lirinine; trifluoroacetic acid; cyc
Synthesis of hernandaline
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, (2008/06/13)
There is disclosed a novel and improved method of synthesizing aporphines utilizing the Pschorr cyclization of 1-(2'-aminobenzyl)-7 hydroxy-1,2,3,4-tetrahydroisoquinolines in place of the corresponding 7-methoxy compounds. In the novel process of the present invention the amino group is diazotized and cyclized in the presence of copper powder.
