497178-55-9 Usage
Description
4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine, also known as thienodiazepine, is a chemical compound that belongs to the benzodiazepine class of drugs. It is a fusion of a thieno and a diazepine ring structure and is known for its psychoactive properties. Thienodiazepines are similar to benzodiazepines in their mechanism of action and have been found to have sedative, anxiolytic, and muscle relaxant effects.
Uses
Used in Pharmaceutical Industry:
4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine is used as a therapeutic agent for the treatment of anxiety, insomnia, and seizures. Its sedative, anxiolytic, and muscle relaxant effects make it a valuable compound in managing these conditions.
However, due to their potential for abuse and addiction, thienodiazepines are regulated substances in many countries, and their use is strictly controlled to ensure the safety and well-being of patients.
Check Digit Verification of cas no
The CAS Registry Mumber 497178-55-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,1,7 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 497178-55:
(8*4)+(7*9)+(6*7)+(5*1)+(4*7)+(3*8)+(2*5)+(1*5)=209
209 % 10 = 9
So 497178-55-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H12N2S/c1-2-5-11-10(4-1)14-8-7-12(15-11)13-6-3-9-16-13/h1-6,9,14H,7-8H2
497178-55-9Relevant articles and documents
Generation of a structurally diverse library through alkylation and ring closure reactions using 3-dimethylamino-1-(thiophen-2-yl)propan-1-one hydrochloride
Roman, Gheorghe
supporting information, p. 70 - 80 (2013/06/27)
3-Dimethylamino-1-(thiophen-2-yl)propan-1-one hydrochloride (2), a ketonic Mannich base derived from 2-acetylthiophene, was used as a starting material in different types of alkylation and ring closure reactions with a view to generate a structurally diverse library of compounds. Compound 2 reacts with S-alkylated dithiocarbamic acid salts and aryl mercaptans to produce dithiocarbamates and thioethers, respectively. The dimethylamino moiety in compound 2 was exchanged with various aliphatic secondary and aromatic primary and secondary amines, whereas monocyclic NH-azoles such as pyrazole, imidazole, 1,2,4-triazole, and tetrazole were N-alkylated by compound 2. Ketones, pyrrole and indoles have been the substrates subjected to C-alkylation reactions by compound 2. Ring closure reactions of compound 2 with a suitable bifunctional nucleophile yielded pyrazolines, pyridines, 2,3-dihydro-1,5-1H-benzodiazepines, 2,3-dihydro-1,5-1H- benzothiazepine, pyrimido[1,2-a]benzimidazole and 4-hydroxypiperidine derivatives.