497181-90-5

Upstream product

• 2428-06-0 2-chloro-5,5-dimethyl-[1,3,2]dioxaphosphinane 
• 497181-77-8 2-[(5,5-dimethyl-[1,3,2]dioxaphosphinan-2-yloxy)-phenyl-methyl]-acrylonitrile 
• 19362-96-0 2-(1-hydroxybenzyl)acrylonitrile 

Downstream Products

• 134259-59-9 (2Z,3E)-2-benzylidene-4-phenylbut-3-enenitrile 

Relevant academic research and scientific papers

New allylphosphonates derived from (OCH2CMe2CH2O)PCl and Baylis-Hillman adducts - Stereochemistry and utility

New allylphosphonates have been prepared; an X-ray structural proof for the major Z-isomer has been given for phosphonate 3. Horner-Wadsworth-Emmons reaction of 3 or 6 (Z isomer) with aromatic aldehydes leads to carbomethoxy/ cyano substituted butadienes. In the reaction using cyanoallylphosphonate 6, use of either Z or E isomer leads to the same E,Z product; stereochemistry of one such cyano product is confirmed by X-ray crystallography. In the reaction of 3 with 4-nitrobenzaldehyde stereochemistry for the (E,E) isomer is confirmed by X-ray crystallography.