497236-39-2Relevant academic research and scientific papers
Total synthesis of lavendamycin by a [2+2+2] cycloaddition
Nissen, Felix,Detert, Heiner
, p. 2845 - 2853 (2011/06/26)
The total synthesis of the bacterial-derived, pentacyclic, antitumor antibiotic lavendamycin has been achieved through a highly convergent strategy. The key step of this synthesis is a ruthenium-catalyzed [2+2+2] cycloaddition of an electron-deficient nit
A highly efficient and flexible synthesis of substituted carbazoles by rhodium-catalyzed inter- and intramolecular alkyne cyclotrimerizations
Witulski, Bernhard,Alayrac, Carole
, p. 3281 - 3284 (2007/10/03)
An A→ABC or A→ABCD ring-formation strategy proves extremely efficient for generating substituted carbazoles ([Eq. (1)]; Ts = tosyl). Inter- and intramolecular alkyne cyclotrimerizations mediated by Wilkinson's catalyst provide substituted carbazoles of re
