758686-23-6

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 220465-91-8 1-(2-aminophenyl)prop-1-yne 
• 1859-70-7 N-(2-acetylphenyl)-4-methylbenzenesulfonamide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 551-93-9 2-aminoacetophenone 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1311160-02-7 N-[(5,8-dimethoxy-7-nitroquinolin-2-yl)ethynyl]-N-[2-(prop-1-ynyl)phenyl]-p-toluenesulfonamide 
• 1311160-18-5 methyl 1-(5,8-dimethoxy-7-nitroquinolin-2-yl)-4-methyl-9-tosyl-β-carboline-3-carboxylate 
• 1311160-28-7 methyl 4-(5,8-dimethoxy-7-nitroquinolin-2-yl)-1-methyl-5-tosyl-γ-carboline-3-carboxylate 
• 497236-39-2 N-ethynyl-N-[2-(prop-1-yn-1-yl)phenyl]-p-toluenesulfonamide 
• 173436-68-5 2-methyl-1-[(4-methylphenyl)sulfonyl]-1H-indole 

Relevant academic research and scientific papers

Iridium-Catalyzed Isomerization/Cycloisomerization/Aromatization of N-Allyl-N-sulfonyl-o-(λ1-silylethynyl)aniline Derivatives to Give Substituted Indole Derivatives

We have developed a one-iridium-catalyst system that transforms N-allyl-N-sulfonyl-2-(silylalkynyl)aniline derivatives, which are 1,7-enynes in which both multiple bonds have a heteroatom, to the corresponding substituted indole derivatives via isomerizat

Total synthesis of lavendamycin by a [2+2+2] cycloaddition

The total synthesis of the bacterial-derived, pentacyclic, antitumor antibiotic lavendamycin has been achieved through a highly convergent strategy. The key step of this synthesis is a ruthenium-catalyzed [2+2+2] cycloaddition of an electron-deficient nit

One-pot synthesis of 2,3-disubstituted N-tosylindoles from o-acyl-N-tosylanilines

The reaction of oacyl-N-tosylanilines with lithium trimethylsilyldiazomethane followed by treatment with t-BuLi and then electrophiles gave 2,3-disubstituted N-tosylindoles in a one-pot process. Georg Thieme Verlag Stuttgart.

New synthesis of 3-substituted indoles using lithium trimethylsilyldiazomethane

Lithium trimethylsilyldiazomethane smoothly reacted with N-tosyl-o-acylanilines to give 3-substituted indoles in good to high yields.

A highly efficient and flexible synthesis of substituted carbazoles by rhodium-catalyzed inter- and intramolecular alkyne cyclotrimerizations

An A→ABC or A→ABCD ring-formation strategy proves extremely efficient for generating substituted carbazoles ([Eq. (1)]; Ts = tosyl). Inter- and intramolecular alkyne cyclotrimerizations mediated by Wilkinson's catalyst provide substituted carbazoles of re