497249-51-1

Basic information

• Product Name: 1-(4-AMINOPHENYL)[1,4]DIAZEPANE
• Synonyms: 1-(4-AMINOPHENYL)[1,4]DIAZEPANE
• CAS NO: 497249-51-1
• Molecular Formula: C₁₁H₁₇N₃
• Molecular Weight: 191.276
• Mol File: 497249-51-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-AMINOPHENYL)[1,4]DIAZEPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-AMINOPHENYL)[1,4]DIAZEPANE(497249-51-1)
• EPA Substance Registry System: 1-(4-AMINOPHENYL)[1,4]DIAZEPANE(497249-51-1)

Safety Data

• Hazardous Substances Data: 497249-51-1(Hazardous Substances Data)

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 505-66-8 1,4-Diazacycloheptane 
• 214124-83-1 1-(4-nitrophenyl)-[1,4]diazepane 

Relevant articles and documents

1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs

A variety of P4 motifs have been examined to increase the binding affinity and in vitro anticoagulant potency of our biphenyl 1-(2-naphthyl)-1H-pyrazole-5- carboxylamide-based fXa inhibitors. Highly potent 2-naphthyl-P1 fXa inhibitors (Ki≤2 nM) with improved in vitro anticoagulant activity (2×TG≤1 μM) and respectable pharmacokinetic properties have been discovered.