4973-20-0Relevant articles and documents
Efficient synthesis of chlorohydrins using ClCH2MgCl·LiCl
Nishimura, Rodolfo H.V.,Toledo, Fabiano T.,Lopes, Jo?o L.C.,Clososki, Giuliano C.
, p. 287 - 290 (2013/02/23)
The mixed lithium-magnesium carbenoid ClCH2MgCl·LiCl was easily generated in THF through the reaction of chloroiodomethane with i-PrMgCl·LiCl at -78 °C. This reagent reacts well with a number of aldehydes to give the corresponding chlorohydrins in good yields.