49781-48-8

Usage

Uses

Used in Pharmaceutical Industry:
2,2-Difluoropropionamide is used as an intermediate in the synthesis of pharmaceuticals for its unique chemical and physical properties that facilitate the creation of various drug compounds.
Used in Agrochemical Industry:
2,2-Difluoropropionamide is used as an intermediate in the synthesis of agrochemicals to help develop effective products for agricultural applications.
Used as a Solvent:
2,2-Difluoropropionamide is used as a solvent in various chemical reactions due to its ability to dissolve a wide range of substances and facilitate desired chemical processes.
Used as a Reagent:
2,2-Difluoropropionamide is used as a reagent in chemical reactions to drive specific transformations and syntheses, taking advantage of its unique properties to achieve desired outcomes in organic synthesis.

Upstream product

• 79-37-8 oxalyl dichloride 
• 373-96-6 2,2-difluoropropanoic acid 

Downstream Products

• 49781-49-9 2,2-difluoropropionitrile 

Relevant academic research and scientific papers

Synthesis method and application of 4-oxo-trans-2-hexenal analogue

The invention discloses a synthesis method and application of a 4-oxo-trans-2-hexenal analogue, and belongs to the technical field of biological prevention and control. The analogues comprise 5-methyl-4-oxo-trans-2-hexenal, 5, 5-difluoro-4-oxo-trans-2-hexenal, 4-oxo-trans-2-hexenoic acid, 4-oxo-trans-2-hexenol and 4-hydroxy-trans-2-hexenal. One or more of the five compounds completely replace 4-oxo-trans-2-hexenal in sex pheromone components of apolygus lucorum, lygus pratensis and apolygus lucorum. The synthesis methods of the 5-methyl-4-oxo-trans-2-hexenal and the 5, 5-difluoro-4-oxo-trans-2-hexenal are found for the first time, the application composition can significantly reduce the release rate of the lure, prolong the trapping time and save the cost, the problem that the 4-oxo-trans-2-hexenal is unstable in the field can be avoided, and the application range of the 5-methyl-4-oxo-trans-2-hexenal is widened. Male insects such as apolygus lucorum, herbage miridae and apolygus lucorum can be trapped and killed more effectively.

MEDICINAL COMPOSITIONS

The present invention relates to an agent for the prophylaxis or treatment of pain, an agent for suppressing activation of osteoclast, and an inhibitor of osteoclast formation, which contains a p38 MAP kinase inhibitor and/or a TNF-α production inhibitor.

Substituted 1,3-thiazole compounds, their production and use

(1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.