497819-05-3

Usage

Furanone class

This chemical compound belongs to the furanone class, which is a group of organic compounds containing a furan ring and a carbonyl group.

Hydroxymethyl and phenylmethoxy functional groups

The presence of these functional groups contributes to the compound's chemical reactivity and physical properties.

E isomer of the 3-position double bond

The presence of this double bond isomer affects the compound's stereochemistry and may influence its chemical properties and reactivity.

Specialized uses

While the exact applications of 2(3H)-Furanone, dihydro-5-(hydroxymethyl)-3-[5-methyl-3-(2-methylpropyl)hexylidene]-5-[ (phenylmethoxy)methyl]-, (3E)- are not specified, its complex structure and classification suggest that it may have specialized uses in certain industries. Further research would be needed to determine its specific properties and potential applications.

Upstream product

• 388621-97-4 5-Benzyloxymethyl-3-[3-isobutyl-5-methyl-hex-(E)-ylidene]-5-(4-methoxy-phenoxymethyl)-dihydro-furan-2-one 
• 100-51-6 benzyl alcohol 
• 213828-29-6 1-(benzyloxy)-2-[(4-methoxyphenoxy)methyl]-4-penten-2-ol 
• 213828-28-5 1-(benzyloxy)-3-(4-methoxyphenoxy)acetone 
• 388622-17-1 (E)-5-[(4-methoxyphenoxy)methyl]-3-[5-methyl-3-(2-methylpropyl)hexylidene]-5-[(phenylmethoxy)methyl]-4,5-dihydrofuran-2-one 
• 924657-63-6 5-benzyloxymethyl-3-(1-hydroxy-3-isobutyl-5-methyl-hexyl)-5-(4-methoxy-phenoxymethyl)-dihydro-furan-2-one 
• 213828-30-9 5-[(4-methoxyphenoxy)methyl]-5-[(phenylmethoxy)methyl]-3,4,5-trihydrofuran-2-one 
• 388621-92-9 5-methyl-3-(2-methylpropyl)hexan-1-one 

Downstream Products

• 946570-38-3 E-{4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxo-2-[(phenylmethoxy)methyl]-2-(2,3-dihydrofuryl)}methyl 3-methylbutanoate 
• 568571-24-4 (E)-N-hydroxy-2,2-dimethyl-N-({4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxo-2-[(phenylmethoxy)methyl]-(2-2,3-dihydrofuryl)}methyl)propanamide 
• 388622-21-7 (E)-5-[(hydroxylamino)methyl]-3-[5-methyl-3-(2-methylpropyl)hexylidene]-5-[(phenylmethoxy)methyl]-4,5-dihydrofuran-2-one 
• 388622-19-3 (E)-5-carbonyl-3-[5-methyl-3-(2-methylpropyl)hexylidene]-5-[(phenylmethoxy)methyl]-4,5-dihydrofuran-2-one 

Relevant academic research and scientific papers

Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators

DAG-lactones represent useful templates for the design of potent and selective C1 domain ligands for PKC isozymes. The ester moiety at the sn-1 position, a common feature in this template, is relevant for C1 domain interactions, but it represents a labile

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP

C1 domain-containing proteins, such as protein kinase C (PKC), have a central role in cellular signal transduction. Their involvement in many diseases, including cancer, cardiovascular disease, and immunological and neurological disorders has been extensi

Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C Ζ and ι from typical C1 domains

To explore the feasibility of developing ligands targeted to the atypical C1 domains of protein kinase C Ζ and ι, we have prepared diacylglycerol lactones substituted with hydrophilic groups on their side chains, which potentially could interact with the

Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKCδ

Diacylglycerol (DAG) lactones have provided a powerful platform for structural exploration of the interactions between ligands and the C1 domains of protein kinase C (PKC). In this study, we report that DAG-dioxolanones, novel derivatives of DAG-lactones,

Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain

The structures of N-hydroxylamides la and lb, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong protein kinase C (PK-C) ligands, were incorrect and correspond instead to esters 2a and 2b, respectively. Here, we report the sy